Medtronic has received Breakthrough Device Designation status from the US Food and Drug Administration (FDA) for the Tyrx absorbable antibacterial driveline wrap, which is intended to securely hold a percutaneous driveline in patients receiving a ventricular assist device (VAD). A...
After surviving a heart attack, the proportion of patients who experience a repeat attack within a year fell between 2008 and 2017, with a greater decline in women than men, according to new research published in the journal Circulation....
Abbott has today announced it has received CE mark approval for its fourth-generation MitraClip transcatheter mitral valve repair system. Known as MitraClip G4, the device is now approved for use in Europe and other regions that recognise CE mark...
A study of US Medicare patients undergoing percutaneous coronary intervention (PCI) has found that the use of intravascular ultrasound (IVUS) resulted in a lower long-term mortality, myocardial infarction (MI), and repeat revascularisation. However, the study by Amgad Mentias (University...
The Cardiovascular Research Foundation (CRF) has announced that over 30 late-breaking trial and science presentations that will be reported at TCT Connect (14–18 October, Virtual). TCT Connect is the the annual scientific symposium of CRF and specialises in interventional...

J Dawn Abbott

J Dawn Abbott is the director of interventional cardiology and an associate professor of medicine in the department of medicine at the Warren Alpert Medical School of Brown University (Providence, USA). She talks to Cardiovascular News about her career...
Aspirin-free prasugrel monotherapy following successful everolimus-eluting stent implantation demonstrated feasibility and safety without any stent thrombosis in selected low-risk patients with stable coronary artery disease (CAD). This was the conclusion of the ASET pilot study published in JACC: Cardiovascular...
VitalConnect has announced the commencement of the TELESTAR-TAVR clinical study—Deployment of Telemedicine for Symptom Tracking And Decrease Readmission Rate in TAVR Patients)—monitoring patients undergoing transcatheter aortic valve replacement (TAVR) using VitalConnect’s VistaSolution LIVE technology. The trial has a primary...
Healthcare professionals should become more familiar with medications that cause arrhythmias, according to a new scientific statement from the American Heart Association (AHA), published in the Association's journal Circulation. “Many commonly used medications can cause irregular heartbeats as a side...
Episode 1: High bleeding risk patients. Who are they and why are they important? Roxana Mehran (New York, USA) – in the first of a special three-part series – talks about how bleeding avoidance strategies are vital because bleeding after...
Cardiac magnetic resonance imaging (MRI) is effective in identifying inflammation of the heart muscle in athletes and can help determine when those who have recovered from COVID-19 can safely return to play in competitive sports, according to a study...
Survey results published to mark Heart Valve Disease Awareness Week show that older Europeans are unaware of the risks of common, serious, but treatable heart valve disease. Data from the latest European Heart Health Survey show that only a...
Multiple studies have shown that fractional flow reserve (FFR) is a valuable modality for assessing the functional significance of coronary lesions. However, it does have limitations—such as the need for a hyperaemic agent. Therefore, other modalities for physiological assessment...
Results of the TIDES-ACS randomised controlled trial, confirming the superior safety and sustained non-inferior efficacy of the Bio-Active Stent technology (Hexacath) at 18 months follow-up versus a drug-eluting stent, have been published. Conducted in 12 international sites, the study randomised...
Medtronic has announced  US Food and Drug Administration (FDA) approval of an early feasibility study (EFS) of the Intrepid transcatheter tricuspid valve replacement (TTVR) system in patients with severe, symptomatic tricuspid regurgitation. This comes on the heels of a...
Researchers from the University of Minnesota, with support from Medtronic, have developed a process for multi-material 3D printing of models of the heart’s aortic valve and the surrounding structures that mimic a real patient. These patient-specific organ models, which include...
Cardiac Dimensions has announced that Australia’s Therapeutic Goods Administration (TGA) has approved its Carillon mitral contour system, a right heart transcatheter mitral valve repair (TMVr) device. The device is designed to treat the primary cause of functional mitral regurgitation...
Fujifilm Sonosite has received 510(k) clearance from the US Food & Drug Administration (FDA) for the company's point-of-care ultrasound portfolio to support healthcare providers in performing accurate cardiac and lung imaging in COVID-19 patients. “point-of-care ultrasound has emerged as a...
Japan and the USA have seen an increase in percutaneous coronary intervention (PCI) procedures, which is driven primarily by a rise in elective PCIs in Japan compared to non-elective in the USA, according to a study in the Journal...
Concept Medical has announced the enrolment of the first patient in the TRANSFORM-1 RCT (TReAtmeNt of Small coronary vessels: Randomized controlled trial FOR MagicTouch sirolimus-coated balloon). TRANSFORM-1 is a prospective, randomised, multicentre, European study focusing on coronary artery lesions in...
CryoLife has announced the acquisition of Ascyrus Medical, developer of the Ascyrus Medical Dissection Stent (AMDS), an aortic arch remodelling device used for the treatment of acute Type A aortic dissections. The addition of the AMDS to CryoLife's product...
The American College of Cardiology (ACC) has announced that its 70th Annual Scientific Session, ACC.21 taking place in Atlanta, USA, will be held across 15–17 May 2021, two months later than the original March dates. “With continued uncertainty surrounding the...
BioVentrix has announced the resumption of cases in the pivotal ALIVE Trial studying Less Invasive Ventricular Enhancement, or LIVE Therapy, using the Revivent TC transcatheter ventricular enhancement system. The first patient procedures completed since elective procedures were paused due...
An invasive approach involving either percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) may be beneficial in high risk stable ischaemic heart disease patients with moderate-to-severe ischaemia and a history of heart failure or left ventricular dysfunction....
According to findings of the POPular CABG trial, the addition of ticagrelor to aspirin after coronary artery bypass graft (CABG) surgery did not reduce the rate of saphenous vein graft (SVG) occlusion. Principal investigator of the trial was Jurriën...
Royal Philips has announced the next-generation of its Azurion image-guided therapy platform, designed to improve the quality and efficiency of interventional procedures. The Azurion platform has been used in over two million procedures worldwide since its introduction three years...
Miracor Medical has announced the closing of a €24 million series-E round of financing. The round was led by a new corporate strategic investor joined by co-investor Yonghua. Current investors Earlybird, Noshaq, Quest for Growth, SFPI-FPIM, SRIW and another...
Atrial fibrillation (AF) is associated with long-term mortality in patients undergoing primary percutaneous coronary intervention (PCI), irrespective of left ventricular (LV) function, a study of the prognostic impact of patients undergoing primary PCI with or without LV dysfunction has...
The POPular TAVI trial has challenged current recommendations on antiplatelet treatment after transcatheter aortic valve implantation (TAVI) in patients not taking oral anticoagulation. Findings of the trial—which concluded that aspirin alone after TAVI reduces bleeding events significantly and does...
Mavacamten (MyoKardia) improves heart function and symptoms in patients with obstructive hypertrophic cardiomyopathy (HCM), according to results of the EXPLORER-HCM trial presented in a Hot Line session at ESC Congress 2020 (Virtual, 29 August–1 September). The findings were published...
Transcatheter mitral valve replacement (TMVR) with the Tendyne device (Abbott) results in favourable left-sided chamber remodelling in the majority of patients one month after implantation, a study presented at the ESC 2020 Congress (Virtual, 29 August–1 September) has concluded....
The European Society of Cardiology (ESC) has issued new guidelines, published online today in the European Heart Journal and on the ESC website, for the management of congenital heart disease and for acute coronary syndromes in patients presenting without...
Empagliflozin reduces the risk of cardiovascular death or hospitalisation for heart failure in patients with heart failure and a reduced ejection fraction (HFrEF), according to findings of the EMPEROR-Reduced trial, to be presented in a Hot Line session today...
Medtronic has announced that the US Food and Drug Administration (FDA) has approved revised commercial labelling for the Evolut transcatheter aortic valve replacement (TAVR) platform that modified a precaution for the treatment of bicuspid severe aortic stenosis (AS) patients...
Meta analysis puts spotlight on optimal DAPT duration Cardiologists warn of long-term impact of COVID-19 News from 2020 PCR e-Course In profile: J Dawn Abbott First 10-year report of TAVI durability indicates a low rate of structural valve...
Meta analysis puts spotlight on optimal DAPT duration Cardiologists warn of long-term impact of COVID-19 News from 2020 PCR e-Course In profile: J Dawn Abbott First 10-year report of TAVI durability indicates a low rate of structural valve...
In this educational supplement, sponsored by Siemens Healthineers, Cardiovascular News explores how advanced imaging systems are being used in modern cath labs. Stephan Achenbach outlines the challenges of the modern cath lab and how these can be addressed. Luise...
The inaugural CX Aortic Vienna meeting will be livestreamed 8–11 September 2020 to an international, online audience, and will include registrant participation, interaction, and polling. The programme will focus on all matters aortic—from the aortic valve to the iliac arteries....
Philips announced today the latest addition to its portfolio of dedicated cardiovascular ultrasound solutions—Affiniti CVx. The system aims to support cardiology departments in delivering better care to more patients with increased efficiency and throughput, Philips said in a press...
Guidelines for reducing the risk of stroke in patients undergoing heart surgery have been detailed in an American Heart Association (AHA) scientific statement, “Considerations for Reduction of Risk of Perioperative Stroke for Adult Patients Undergoing Cardiac and Thoracic Aortic...
The Heart Rhythm Society has announced the publication of the inaugural issue of the Cardiovascular Digital Health Journal. The new journal focuses on the emerging field of digital medicine across all areas of cardiology. David McManus (UMass Memorial Medical...
The risk of in-hospital death and in-hospital heart failure increased for ST-elevation myocardial infarction (STEMI) patients in China during the early stages of the COVID-19 pandemic, according to research published in the Journal of the American College of Cardiology...
A study comparing recommendations from a heart team versus those of an interventional cardiologist for the treatment of patients with multivessel coronary artery disease (CAD) has found differing recommendations in up to one-third of cases. According to the author of...
  Representation of women leading heart failure research remains limited, according to a study published in Circulation: Heart Failure, which may create a barrier to greater diversity among clinical trial participants. The analysis, which was led by Nosheen Reza, Perelman School...
Transcatheter tricuspid valve replacement in the setting of trans-tricuspid pacemaker leads without extraction or re-replacement can be performed safely with a low risk of complications, a study published in JACC: Cardiovascular Interventions has found. The study, authored by Jason...
Royal Philips has announced the introduction of OmniWire, a solid core pressure wire for coronary artery interventional procedures. With a solid core construction, physicians can more easily manoeuvre the wire in the patient’s circulatory system to measure blood pressure...
Ahead of the 2020 European Society of Cardiology (ESC) Congress, taking place from 29 August–1 September, the event’s scientific chair Marco Roffi (University Hospitals of Geneva, Geneva, Switzerland) offers Cardiovascular News a preview of how the digital event is...
COVID-19 patients with cardiovascular comorbidities or risk factors are more likely to develop cardiovascular complications while hospitalised, and more likely to die from COVID-19 infection, according to a new study published in PLOS ONE. For most people, the Novel Coronavirus...
Translumina has announced the publication of 10-year follow-up data on its dual-drug polymer-free drug-eluting stent (DES), VIVO ISAR, in the Journal of the American College of Cardiology (JACC), describing the device’s efficacy and safety profile. Many studies have proven that...
With whole sections of society migrating online during the COVID-19 pandemic, e-learning has risen to the fore in medical education. Thomas Binder, founder and chairman of 123sonography.com considers how online learning has become a staple for healthcare professionals during...
Mental stress and anger may have clinical implications for patients with heart failure according to a study published in the Journal of Cardiac Failure. In this study of patients who had heart failure with reduced ejection fraction, the authors evaluated...
Biosensors announced today the enrolment of the first patient in REFORM—a prospective, randomised, non-inferiority trial to determine the safety and efficacy of the Biolimus A9 drug coated balloon for the treatment of in-stent restenosis: first-in-man trial. This trial is...
A US survey released by patient advocacy group Heart-Valve-Surgery.com, with support by Medtronic, has found that nearly half (49%) of heart valve patients say return to active living is a key factor in their treatment decision. The survey of more...
InnovHeart—developer of novel transcatheter mitral valve replacement (TMVR) systems for the treatment of mitral valve disease—has announced the closing of a US$23.8 million round of equity financing. Proceeds from the financing will be used to complete the first-in-human clinical evaluation...
The Journal of the American Heart Association (JAHA) has retracted a paper published in March 2020, which drew criticism due to its conclusions about race and the role of affirmative action within cardiology.  The paper, authored by Norman C Wang, associate professor of medicine at the University of Pittsburgh,...
Thirty-day clinical outcomes from the FORWARD PRO international study of the Evolut Pro (Medtronic) self-expanding transcatheter aortic valve, published in EuroIntervention, have confirmed the safety and efficacy of the device with an external pericardial wrap. Evolut Pro is a repositionable,...
CardioMech, developer of a transfemoral, transseptally delivered mitral valve repair technology, announced today it has closed on its Series A financing led by a non-disclosed strategic investor together with healthcare specialist investor Hadean Ventures and Investinor. The US$18.5M financing...
A meta-analysis of 24 randomised controlled trials assessing dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) with drug-eluting stents shows a net clinical benefit in favour of short-term DAPT followed by P2Y12 inhibitor monotherapy, instead of aspirin, in...
Eko has announced a collaboration with AstraZeneca to accelerate the development of digital health tools for the earlier screening of cardiovascular diseases, including heart failure. Through the collaboration, AstraZeneca and Eko will explore accelerating the development of Eko algorithms,...
The US Food and Drug Administration (FDA) has issued an emergency use authorisation (EUA) for left-sided Impella heart pumps to provide left ventricular unloading and support to COVID-19 patients who are undergoing extracorporeal membrane oxygenation (ECMO) treatment and develop...
In this educational supplement, sponsored by Boston Scientific, Cardiovascular News explores the use of transcatheter aortic valve implantation (TAVI), including latest developments in techniques and approaches. Lars Søndergaard charts the evolution of TAVI and considers patient tailored TAVI to...
As interventional cardiology continues to grow with higher risk patients and more complex coronary, writes Rajan Patel (Ochsner Clinic Foundation, Jefferson, USA), the need for educational resources to support clinicians with advanced techniques becomes ever-greater. He outlines the CAMP...
A German study of recently-recovered COVID-19 patients examined using magnetic resonance imaging (MRI) revealed cardiac involvement in 78% of patients, and ongoing myocardial inflammation in 60%. Published online in JAMA: Cardiology, the study’s findings indicate the need for ongoing...
A three-year, investigator-led, prospective study of Japanese patients who received an Impella heart pump has found that the use of Impella is associated with a 77% survival rate at 30 days in acute myocardial infarction cardiogenic shock patients. The...
One-year outcomes of mitral valve-in-valve replacement using the Sapien 3 (Edwards Lifesciences) transcatheter heart valve have been published in JAMA: Cardiology, reporting low all-cause mortality at 30 days (5.4%) and one-year (16.7%), and a 96.8% procedural success rate. In the...
Keystone Heart has announced completion of the first worldwide commercial case using the TriGUARD 3 cerebral embolic protection (CEP) device. Pieter Stella, assistant professor, Medical Department of Cardiology, at UMC Utrecht, Utrecht, the Netherlands, performed the transcatheter aortic valve...
Use of non-steroidal anti-inflammatory drugs (NSAIDs) to treat first-time heart attack patients significantly increased the risk for cardiovascular and bleeding events post-heart attack in a nationwide Korean study, published in the Journal of the American College of Cardiology. “To the...
The American College of Cardiology (ACC) is expanding its JACC family of peer-reviewed journals to include JACC: Asia, which will publish original manuscripts focused on Asian populations and by Asian authors. The journal will be the first region-specific cardiovascular...
The US Food and Drug Administration (FDA) has approved one-way digital data streaming during patient support from Abiomed’s Automated Impella Controller (AIC), the external console used with Impella heart pumps. The data streaming capability is facilitated through the Impella Connect...
Aortic valve replacement, using either transcatheter aortic valve implantation (TAVI) or surgical aortic valve replacement (SAVR) approaches appear to be similarly effective for males and females at intermediate surgical risk, a post-hoc analysis of the randomised SURTAVI (Surgical Replacement...
Caption Health, a developer of medical artificial intelligence (AI) technology, has received US Food and Drug Administration (FDA) 510(k) clearance for an updated version of Caption Interpretation, which enables clinicians to obtain quick, easy and accurate measurements of cardiac...
MyoKardia has announced that the US Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation to mavacamten, a novel, oral, allosteric modulator of cardiac myosin, for the treatment of symptomatic, obstructive hypertrophic cardiomyopathy. The FDA's Breakthrough Therapy Designation is...
Digital health and artificial intelligence (AI) company Eko has been awarded a US$2.7 million Small Business Innovation Research (SBIR) grant by the National Institutes of Health (NIH). The grant will fund the continued collaborative work with Northwestern Medicine Bluhm...
Genetic testing and counselling for inherited cardiovascular diseases may help patients and their families make informed decisions about managing their heart health, according to Genetic Testing for Inherited Cardiovascular Diseases, a scientific statement from the American Heart Association (AHA),...
Findings of a US investigation of clinician race and gender bias in decision-making around heart failure therapies suggests that African American women may be judged more harshly by appearance and adequacy of social support than their peers. Published in...
Scitech has announced that the Inspiron coronary sirolimus eluting stent has received CE mark approval. The device is a third generation drug eluting stent designed to create a fast and homogeneous endothelialisation. According to a press release from Scitech, the...
Boston Scientific has received US Food and Drug Administration (FDA) approval for the Watchman FLX left atrial appendage closure (LAAC) device. The device is indicated to reduce the risk of stroke in patients with non-valvular atrial fibrillation (NVAF) who...
LifeSignals Group has announced that it has received US Food and Drug Administration (FDA) 510(k) clearance for the LifeSignals ECG Remote Monitoring Patch platform. The platform is a wireless remote monitoring system intended for use by healthcare professionals for the...
Azeem Latib (New York, USA) spoke to Cardiovascular News about a sub-analysis of the Onyx ONE study. The study randomised 2,000 patients who were high-risk for bleeding in a 1:1 fashion to receive either the durable-polymer Resolute Onyx drug-eluting...
  Philipp Lurz (Leipzig, Germany) speaks to Cardiovascular News about the TRILUMINATE trial which looked to assess the safety and efficacy of the Triclip device (Abbott) in patients with tricuspid regurgitation. The one-year data showed that the procedure is “very safe”...
LivaNova has announced that the advanced Perceval Plus sutureless surgical aortic heart valve is now available for commercial release in Europe, having successfully completed a one-year limited launch with initial real-world clinical data gathering. The next-generation valve facilitates minimally invasive...
Women taking beta blockers for hypertension with no prior history of cardiovascular disease have a nearly 5% higher risk for heart failure than men when they present to hospital with acute coronary syndrome, according to research published in Hypertension,...
A rise in the number of out-of-hospital cardiac arrests (OHCAs) correlated with a fall in the number of acute coronary syndrome hospitalisations during the COVID-19 surge in the New York metropolitan area, according to a research letter published in...
Edwards Lifesciences has announced approval from the US Food and Drug Administration (FDA) for the KONECT RESILIA aortic valved conduit (AVC), a ready-to-implant solution for bio-Bentall procedures, a surgery that involves replacement of a patient's aortic valve, aortic root...
The American Heart Association (AHA) has announced that its 2020 Scientific Sessions will be presented as a 100% virtual experience in light of the impact of the COVID-19 pandemic. The event will be held November 13‒17, with registration opening...
Around half of COVID-19 patients who received an echocardiogram in-hospital showed abnormalities in heart function, according to a prospective international survey funded by the British Heart Foundation and published in the European Heart Journal‒Cardiovascular Imaging. The study, authored by...
Revamp Medical has announced that the US Food and Drug Administration (FDA) has granted Breakthrough Device Designation for the Doraya device, a temporary intravenous catheter. The device flow regulator mechanism is designed to temporarily reduce Central Venous Pressure and improve...
ACIST Medical Systems has announced the global launch of its ACIST Navvus II Rapid Exchange FFR MicroCatheter, the second-generation microcatheter for use with its ACIST RXi Rapid Exchange FFR system. Fractional flow reserve (FFR) measurements provide assessment of arterial lesion...
Venus Medtech has announced a collaboration to bring Pi-Cardia's Leaflex technology to China. Pi-Cardia's Leaflex catheter performs mechanical scoring of valve calcification, restoring leaflets' mobility and improving valve haemodynamics. The Leaflex catheter is to be used for patients who are...
The European Association of Percutaneous Cardiovascular Interventions (EAPCI) has published a consensus document on ischaemia with non-obstructive coronary arteries (INOCA), offering guidance on the diagnostic approach and management. Published simultaneously in European Heart Journal and EuroIntervention by a task...
Janarthanan Sathanathan (Center for Heart Valve Innovation, St Paul’s Hospital, Vancouver, Canada) and others report in Catheterization & Cardiovascular Interventions that the 10-year rate of bioprosthetic structural valve failure and valve failure was low in patients who had undergone...
Paragonix Technologies presented new clinical data at the American Transplant Congress (ATC) on the successful use of the Paragonix SherpaPak cardiac transport system for high-risk donor hearts at the Medical University of Vienna (Vienna, Austria), a leading European heart transplant...
MedAlliance has announced enrollment of the first patient in its study of Selution SLR 014” drug eluting balloon (DEB) for the treatment of in-stent restenosis. According to the company, this is the first DEB to be accepted by the...
Jens Erik Nielsen-Kudsk (Aarhus, Denmark) speaks to Cardiovascular News about a propensity score-matched study which examined left atrial appendage occlusion (LAAO) compared with novel oral anticoagulants (NOACs) in atrial fibrillation (AF) patients with a high risk of stroke and...
Black patients who undergo percutaneous coronary intervention (PCI) are at an increased risk for major adverse outcomes, including death, compared to white patients, according to a study published in JACC: Cardiovascular Interventions. A press release from the American College...
Ancora Heart has been given US Food and Drug Administration (FDA) approval of its investigational device exemption (IDE) application for the CorCinch-HF pivotal study, which is designed to evaluate the safety and efficacy of the AccuCinch Ventricular Repair System...
The American Heart Association (AHA) has named Mitchell SV Elkind as president of the organisation for its 2020–2021 fiscal year, which began on 1 July. In a press release, the AHA says that Elkind is a professor of neurology and...
Using an Impella device is contraindicated in patients with severe aortic stenosis with a valve area of 0.6cm2. Karuppiah Arunachalam and his mentor Rizwan Sardar (both Aultman Hospital, Canton, USA) presented their feasibility study on Impella CP-assisted high-risk percutaneous...
NuVera Medical has announced the initiation of the company's first-in-human clinical trial to evaluate the performance of its NuVision intracardiac echocardiography (ICE) catheter. The first study participant was successfully treated this month for an atrial septal defect by principal...
US national hospital- and surgeon-level inverse volume–outcome associations were observed for 30-day and one-year mortality after mitral valve surgery for primary mitral regurgitation, according to a study published in JAMA Cardiology. Authors Vinay Badhwar (Department of Cardiovascular and Thoracic...
Patients who have trouble sleeping after heart bypass surgery should go for a morning walk, according to research presented on ACNAP Essentials 4 You, a scientific platform of the European Society of Cardiology (ESC). In a press release from the...
US Food and Drug Administration (FDA) Investigational Device Exemption (IDE) approval has been granted for the Carag Bioresorbable Septal Occluder (CBSO). The CE-marked CBSO is a transcatheter septal occluder with a bioresorbable, metal-free framework. Carag's first US trial is designed...
Mid-term data continue to show non-inferiority of resting instantaneous wave-free ratio (iFR) when tested against hyperaemic fractional flow reserve (FFR), said Javier Escaned (Hospital Clinico San Carlos, Madrid, Spain) who reported a pooled, nearly 4,500 patient-level analysis of DEFINE...
A subanalysis of the Onyx One study found that cardiac death was significantly higher in patients who received single antiplatelet therapy with a P2Y12 inhibitor following percutaneous coronary intervention (PCI) than those who received single antiplatelet therapy with aspirin....
Left atrial appendage occlusion (LAAO) using the Amplatzer Amulet (Abbott) device has a high implant success rate and a low procedural complication rate in a population at high risk of stroke and major bleeding, one-year outcomes from a roll-in...
MedAlliance has been awarded CE mark for the Selution SLR 014 percutaneous transluminal coronary angioplasty (PTCA), a novel sirolimus drug eluting balloon (DEB), for the treatment of coronary artery disease. This includes indications for both de-novo lesions and in-stent...
BioCardia has announced that it has resumed cases in the CardiAMP Heart Failure Trial. The first patient procedure completed since elective procedures were paused due to COVID-19 took place at Morton Plant Hospital in Clearwater, Florida, USA, this month....
The feasibility, safety, and efficiency of transcatheter aortic valve implantation (TAVI) using a self-expanding platform in bicuspid aortic valves has been confirmed by the BIVOLUT X registry, Didier Tchétché (Clinique Pasteur, Toulouse, France) told PCR e-Course 2020 (25–27 June)....
According to a press release, one-year total population clinical outcome data from e-ULTIMASTER—the world’s largest registry of patients treated with a drug-eluting stent—can reinforce “the trust cardiologists worldwide have in the Ultimaster drug-eluting stent (Terumo)” while providing valuable insight...
The FABOLUS FASTER trial, which was presented at PCR e-Course 2020 and simultaneously published in Circulation, shows that cangrelor provides inferior inhibitor of platelet aggregation (IPA) to tirofiban in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary...
Felice Gragnano (Inselspital, Bern University Hospital, Bern, Switzerland) outlined at PCR e-Course 2020 the initial results with the CoFlo system (CorFlow Therapeutics). He explained that the system was “safe, easy to use”, follows percutaneous coronary intervention (PCI) workflow and...
Left atrial appendage occlusion (LAAO) improves clinical outcomes including ischaemic stroke, major bleeding and all-cause mortality, in atrial fibrillation (AF) patients with a high risk of stroke and major bleeding, compared to the use of novel oral anticoagulants (NOACs)....
Sripal Bangalore (New York University Grossman School of Medicine, New York, USA) presented the results of a late-breaking meta-analysis of randomised trials (including the recently published ISCHEMIA and ISCHEMIA-CKD) that compared routine revascularisation with an initial conservative strategy at...
One-year results from the TRILUMINATE study show that TriClip (Abbott) transcatheter therapy for symptomatic moderate or greater tricuspid regurgitation (TR) results in durable reduction of regurgitation, with few major adverse events, and improvement in functional and clinical outcomes. Phillip Lurz...
Clinical and imaging results at 12 months for the DynamX Novolimus-Eluting Coronary Bioadaptor system (Elixir Medical) have demonstrated “excellent” safety and efficacy, a late-breaking trial session at the PCR e-Course 2020 event (25–27 June) has been told. Stefan Verheye (Antwerp...
A systematic two-stent approach in complex coronary bifurcation lesions is associated with a significantly greater improvement in clinical outcomes at one year than provisional stenting, according to the DEFINITION II study, presented at a late-breaking trial session at the...
Patients who crossed over from the sham control arm of the RADIANCE-HTN SOLO trial to the renal denervation arm after 12 months of elevated blood pressure had decreased daytime ambulatory systolic blood pressure at both two and six months...
Full one-year follow-up from the Evolut Low Risk trial has upheld earlier findings from the study, demonstrating that transcatheter aortic valve implantation (TAVI) is non-inferior to surgical aortic valve replacement (SAVR) for all-cause mortality or disabling stroke at two...
Long-term clinical outcomes, including mortality, following an aortic valve-in-valve procedure may be affected by the size of the original degenerated bioprosthetic valve, according to findings from the Valve-in-Valve International Data (VIVID) Registry which were released at the PCR e-Course...
Use of the transseptal Evoque transmitral valve replacement (TMVR) system (Edwards Lifesciences) has been shown to be feasible in a first-in-human experience, a hotline session at PCR e-Course 2020 (25-27 June) has been told. The findings, presented by John...
A comprehensive evaluation of mitral valve-in-valve (ViV) and valve-in-ring (ViR) procedures has found that residual mitral stenosis and/or mitral regurgitation were “relatively common”, and that both were associated with a need for repeat valve replacement. Significant residual mitral regurgitation...
The American College of Cardiology (ACC) and Society for Vascular Surgery (SVS) are collaborating on a single vascular registry, according to a press release, to harness the strengths of both organisations in improving care and outcomes of patients with...
Miracor Medical has announced the award of the CE mark for its latest generation of PiCSO Impulse Catheter and PiCSO Impulse Console, which is indicated for the treatment of anterior STEMI patients. It says the new system features improvements...
Medtronic has been awarded CE mark for the use of the Evolut transcatheter aortic valve implantation (TAVI) system for patients with severe native aortic stenosis who are at low surgical risk. The Evolut TAVI platform has also received a...
Voice analysis by a smartphone app can identify lung congestion in heart failure patients, allowing early intervention before their condition deteriorates, a study presented on HFA Discoveries, a scientific platform of the European Society of Cardiology (ESC) has found. “Speech...
Proximo Medical has announced a partnership with digital health company Coala Life in select US markets. According to a press release from Proximo Medical, it provides a business acceleration solution to addresses medical device commercialisation challenges among startup and...
Abiomed has launched a virtual physician education programme, CAMP PCI (Coronary artery and myocardial protected percutaneous coronary intervention), to improve high-risk PCI patient outcomes. A press release from the company outlines that the digital education platform was developed to...
Trainee interventional cardiologists have raised concerns that reductions in patient numbers undergoing cardiac catheterisation procedures during the pandemic is impeding their professional development.  Sabeeda Kadavath (University of Arkansas for Medical Sciences, Little Rock, USA) and colleagues from the Cardiovascular Fellows...
Telemedicine has come into its own during the pandemic. Sameer Mehta details the STEMI treatment strategy of the Latin America telemedicine infarct network (LATIN), and shares lessons learnt. The response to the coronavirus pandemic has led to seismic developments around...
Blue Sail Medical has completed the acquisition of Swiss based company NVT AG. The closure of the deal was publicly announced on the Shenzhen Stock Exchange on the 9 June 2020, and a press release from Blue Sail Medical...
MicroPort has been given CE approval for its PathBuilder Steerable Introducer, PathBuilder Transseptal Guiding Introducer and PathBuilder Transseptal Needle. A company statement outlines that the PathBuilder range of products helps to build a pathway from the femoral vein into atrium,...
The British Heart Foundation (BHF) is calling on the Government and the NHS to urgently address the immediate needs of heart and circulatory patients who have had care postponed during the coronavirus pandemic. The charity made its statement after...
Abiomed has received investigational device exemption (IDE) from the US Food and Drug Administration (FDA) for an early feasibility study with a first-in-human trial of Impella ECP (expandable cardiac power), a 9 French (Fr) heart pump. It will be...
Biosensors International Group has announced the appointment of Keith G Oldroyd to the post of chief medical officer.  A press release from the company details that Oldroyd was a consultant interventional cardiologist at the West of Scotland Regional Heart...
Collaboration between cardiothoracic and vascular surgeons is key to achieving success in aortic arch interventions, a session at CX 2020 LIVE has concluded. Speakers presenting in a session entitled Aortic Arch Consensus and Stroke from Thoracic Endovascular Procedures (STEP)...
Medtronic has received the CE mark for a one-month dual antiplatelet therapy (DAPT) indication for high bleeding risk patients implanted with the Resolute Onyx drug-eluting stent. A press release reports that for high bleeding risk patients, this new, first-of-its-kind...
Clinical and echocardiographic outcomes at 30 days and one year were similar between patients with bicuspid and tricuspid aortic stenosis following transcatheter aortic valve implantation (TAVI) with a self-expanding valve in a recent analysis from the TVT Registry. Researchers...

Vinod Thourani

Mitral and tricuspid valve technologies, aortic valve replacement, and the value of the heart team are among the issues that Vinod Thourani (Marcus Valve Center, Piedmont Heart Institute, Atlanta, USA) tackles, as he reflects on his career for Cardiovascular...
The American College of Cardiology (ACC) is to host a weekly virtual meeting— the Summer COVID-19 Education Series—to provide the healthcare community with actionable insights and solutions that will address key clinical and operational concerns and challenges during the...
The European Society of Cardiology (ESC) has announced that the HFA Discoveries online event will be running six days of live sessions from 5 to 19 June, looking at prevention and treatment strategies in heart failure. The sessions will...
COVID-19 linked to a near 40% drop in STEMI cases in US cath labs Survey provides insights into how to tackle COVID-19 elective backlog Profile of Vinod Thourani Transcatheter mitral valve implantation
COVID-19 linked to a near 40% drop in STEMI cases in US cath labs Survey provides insights into how to tackle COVID-19 elective backlog Profile of Vinod Thourani Transcatheter mitral valve implantation
A Bayesian analysis of EXCEL and other randomised controlled trials comparing coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI) in left main coronary artery disease (LMCAD) suggests that PCI was associated with inferior long-term results for all...
LivaNova have presented the first data from the Perceval sutureless implant versus standard-aortic valve replacement (PERSIST-AVR) clinical study at the 100th Annual Meeting of the American Association of Thoracic Surgery (AATS), which took place online 22–23 May 2020. A...
CeloNova BioSciences has announced that it has successfully completed enrolment into the COBRA REDUCE randomised controlled trial to evaluate the safety and efficacy of the Cobra PzF nanocoated coronary stent (NCS) in percutaneous coronary intervention (PCI) with 14-day dual...
The annual Transcatheter Cardiovascular Therapeutics (TCT) meeting has become the latest in a long line of conferences this year that has had to convert their physical meeting into a virtual one. The meeting, which was to be held between...
The Society for Cardiovascular Angiography and Interventions (SCAI) and the Canadian Association of Interventional Cardiology (CAIC) have launched a new registry—NACMI (North American COVID-19 ST-segment elevation myocardial infarction registry)—to better understand the presentation of ST-segment elevation in patients with...
According to research published in JACC: Heart Failure, patients with heart failure who experience low health literacy are at an increased risk of hospitalisation and mortality. A press release reports that this finding has significant clinical and public health...
A press release reports that the Society of Cardiovascular Computed Tomography (SCCT) will present the 2020 Gold Medal Award to John Lesser (Minneapolis Heart Institute/Abbott Northwestern Hospital, Minneapolis, USA) at the SCCT 15th Annual Scientific Virtual Meeting on July...
According to a survey published in the Journal of Occupational and Environmental Medicine, NHS staff working during the pandemic are showing signs of mild depression. The survey also indicates that a large majority (81%) of workers fear contracting COVID-19...
In JACC: Heart Failure, Mathias Orban (Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany) and colleagues report that transcatheter tricuspid valve repair for the management of severe tricuspid regurgitation is associated with reduced heart failure hospitalisations...
Several studies have suggested that, across all countries, COVID-19 mortality is higher in people of colour. Keith C Ferdinand (Tulane University School of Medicine, New Orleans, USA) and his colleague, Samar Nasser, recently wrote in the Journal of the...
Data from more than 1,000 patients presented during the virtual Society for Cardiovascular Angiography and Interventions (SCAI) 2020 Scientific Sessions (14–16 May, Eastern Time) demonstrates Impella (Abiomed) reduced in-hospital mortality when placed before a non-emergent percutaneous coronary intervention (PCI)...
Medtronic has that announced Jeffrey J Popma (Harvard Medical School; Beth Israel Deaconess Medical Center, Boston, USA) will join the company as vice president and chief medical officer supporting the coronary, renal denervation, and structural heart businesses. A press...
Edwards Lifesciences has received the CE mark for the PASCAL transcatheter valve repair system for the treatment of European patients with tricuspid regurgitation. A press release reports that the PASCAL system is indicated in Europe for the percutaneous reconstruction of...
A study published in Circulation: Cardiovascular Interventions shows that robotic percutaneous coronary intervention with the CorPath GRX system (Corindus Vascular Robotics, Siemens Healthineers) reduces patient exposure to radiation by 20% compared to manual PCI with no increase in fluoroscopy...
A late-breaking clinical trial presented at the virtual Society for Cardiovascular Angiography and Interventions (SCAI) 2020 Scientific Sessions (14–16 May, Eastern Time) demonstrated strong long-term haemodynamic and safety outcomes for the Melody transcatheter pulmonary valve (Medtronic). Additionally, results from...
Weili Xu (Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China) and colleagues report in the Journal of the American College of Cardiology that people with a higher risk of developing cardiovascular disease have...
A study presented at the virtual Society for Cardiovascular Angiography and Interventions (SCAI) 2020 Scientific Sessions (14–16 May, Eastern Time) has found that a non-fasting strategy prior to cardiac catheterisation is non-inferior to a traditional fasting strategy in terms...
A study presented yesterday at the virtual Society for Cardiovascular Angiography and Interventions (SCAI) 2020 Scientific Sessions (14–16 May, Eastern Time) indicates that the addition of icosapent ethyl to statin therapy in patients with elevated triglycerides and increased cardiovascular...
A novel, groundbreaking trial has examined the viability of telemedicine for remote guidance of a population-based ST-segment elevation myocardial infarction (STEMI) programme reaching more than 100 million patients. The study, presented as late-breaking science during the SCAI 2020 Scientific...
PCR has announced a new online initiative—e-Course 2020—that is to run online from 25 June 27 June. According to the PCR website, the course “will be sharing the latest scientific news and best practice for the full benefit of...
The Society for Cardiovascular Angiography and Interventions (SCAI) has published a position statement addressing optimal percutaneous coronary intervention (PCI) treatment of patients with complex coronary artery disease. The position statement was presented today during the SCAI 2020 Scientific Sessions...
MedAlliance has announced the award of its second CE mark: Selution SLR 014 percutaneous transluminal angioplasty balloon, which is a novel sirolimus-eluting balloon for the treatment of coronary arterial disease. This includes indications for both de novo lesions as...
A survey published in The Annals of Thoracic Surgery find that despite being in an intensely demanding and competitive specialty, cardiothoracic surgeons report being extremely satisfied with their jobs—more so than ever before. Administered by The Society of Thoracic...
The American College of Cardiology (ACC) is start to collecting COVID-19 data through the NCDR Chest Pain-MI and CathPCI registries with the aim of capturing the relationship between COVID-19 and heart disease and maximise data on the cardiac impact...
Royal Philips has announced that it has received 510(k) clearance from the US Food and Drug Administration (FDA) to market a wide range of its ultrasound solutions for the management of COVID-19-related cardiac and lung complications. Handheld and portable ultrasound...
The US Food and Drug Administration (FDA) has expedited clearance of an update to software from Caption Health, a medical artificial intelligence (AI) company, that is designed to aid frontline healthcare workers to perform diagnostic-quality cardiac ultrasounds. Following a...
Two-year data from the BIONYX trial show that all-comer patients who underwent percutaneous coronary intervention (PCI) with Resolute Onyx (Medtronic) had a similar rate of target vessel failure to those who underwent PCI with Orsiro (Biotronik). Additionally, unlike the...
According to a statement, Heart Valve Voice US is “deeply concerned” that the patient perspective was omitted from the recent guidance on resuming cardiovascular procedures published the Journal of the American College of Cardiology. The guidance was endorsed by...
A joint UK-US research team is applying an artificial intelligence (AI) system to map for the first time how the COVID-19 virus attacks the heart with such deadly impact. This week, British health-tech company Ultromics and Mayo Clinic in...
BioCardia has announced data from a recent animal study performed that, according to a press release, demonstrate meaningful improvements in heart function for patients treated with its allogenic neurokinin 1 receptor positive mesenchymal stem cell (NK1R+ MSC) programme for...
Corresponding author Valentin Fuster (Mount Sinai Heart, New York, USA) and colleagues report in the Journal of the American College of Cardiology that hospitalised COVID-19 patients treated with anticoagulants had improved outcomes both in and out of the intensive...
Boston Scientific has announced positive 12-month results from the PINNACLE FLX clinical trial assessing the safety and efficacy of the next-generation WATCHMAN FLX Left Atrial Appendage Closure (LAAC) Device for patients with non-valvular atrial fibrillation (NVAF). Presented as a...
  A BIBA MedTech Insights survey indicates that 50% of centres performing structural heart procedures believe that they will need to increase the number of operating days per week to manage the elective cases that have been put on hold...
Vishal Luther (final year cardiology registrar/ Electrophysiology fellow, Imperial College Healthcare NHS trust, London NW Thames Deanery, UK) and his colleague Balrik Kailey (cardiology registrar) have organised a programme of webinars—CardioWebinars during COVID19—to help cardiology fellows continue education over...
The European Society of Cardiology (ESC) is, for the first time in its 70-year history, to hold its annual meeting (ESC Congress) 100% online. A press release states that the move follows an announcement from the Dutch government banning...
According to recently presented TICO trial data, a press release reports, patients with acute coronary syndrome treated with the Orsiro drug-eluting stent (Biotronik) benefit from stopping aspirin three months after stenting and continuing only with ticagrelor monotherapy. Yang Soo...
ZOLL Medical has received CE Mark approval to market and distribute its SuperSaturated oxygen (SSO2) therapy system in Europe. A press release reports that SSO2 therapy provides interventional cardiologists with the first and only clinically proven treatment beyond percutaneous...
The Society of Cardiovascular Computed Tomography (SCCT) has announced plans to hold its annual scientific meeting in a virtual format. The in-person meeting, which was to take place in Seattle (USA), was cancelled because of coronavirus-related restrictions on travel...
The American College of Cardiology (ACC) and other North American cardiology societies, including the Canadian Association of Interventional Cardiology (CAIC), have issued guidance on ethically and safely reintroducing invasive cardiovascular procedures after the peak of COVID-19 has passed. The...
A study presented at EAPC Essentials 4 You—a virtual scientific platform of the European Society of Cardiology (ESC)—found that the top three myocardial infarction symptoms in both women and men are chest pain, sweating, and shortness of breath. These...
LifeSignals has received CE mark approval for the LifeSignals ECG Remote Monitoring Patch, a disposable wireless remote monitoring system, intended for use by healthcare professionals for continuous collection of Electrocardiography (ECG) and heart rate monitoring in ambulatory, hospital, healthcare...
A necklace that detects abnormal heart rhythm will be showcased for the first time on EHRA Essentials 4 You, a scientific platform of the European Society of Cardiology (ESC). According to the study's author, Elmeri Santala from the University of...
PCR has issued a statement announcing that it is officially cancelling the 2020 physical EuroPCR congress, which was due to take place in two weeks’ time (19–22 May, Paris, France). According to the statement, the “sanitary and legal environment”—specifically,...
Recent studies have suggested that during the pandemic, there has been a drop in ST-segment elevation myocardial infarction (STEMI) cases. This has led to fears that patients are not seeking medical attention when they experience symptoms of a STEMI...
A new study has found no significant differences in hospital mortality between multivessel percutaneous coronary intervention (PCI) and culprit-vessel only PCI for the management of cardiogenic shock patients who had received early mechanical circulatory support. These findings suggest that,...
Before the 1940s, the prognosis for babies born with complex congenital heart disease was dismal. Less than 10% of these children survived to adulthood. However, since then, major breakthroughs in the detection and treatment of congenital conditions have greatly...
Prism Schneider (Cumming School of Medicine, University of Calgary, Calgary, Canada) and others write in a commentary in the Canadian Medical Association Journal—because of an increase in domestic violence during the pandemic—healthcare providers should be aware of the signs...
Abiomed (maker of the Impella heart pump) has acquired Breethe, developer of a novel extracorporeal membrane oxygenation (ECMO) system. A press release reports that the acquisition will complement and expand Abiomed’s product portfolio to more comprehensively serve the needs of...
New guidance from the American Academy of Neurology (AAN) recommends the closure of a patent foramen ovale (PFO) for some people who have had a stroke. The updated practice advisory has been published online in Neurology. Previous guidance concluded...
On 18 March, the Centers for Medicare & Medicaid Services (CMS) recommended “limiting non-essential care and expanding surge capacity into ambulatory surgical centres and other areas” to conserve resources and staff for managing COVID-19 patients. However, in a statement...
Robocath, which designs, develops and commercialises cardiovascular robotic systems for the treatment of vascular diseases, has secured €40 million ($43M) in a series C round of financing. A press release reports that this was led by MicroPort Scientific Corporation,...
iRhythm Technologies has announced a virtual platform to support patients and clinicians in the wake of COVID-19 by offering home enrolment for the company’s Zio XT and Zio AT heart monitoring devices. Since patients with heart conditions are a particularly...
Boston Scientific, according to a press release announcing the company’s Q1 2020 financial results, has received the CE mark for its Acurate neo2 aortic valve system. The press release reports that the transcatheter aortic valve implantation (TAVI) system builds...
The Society for Cardiovascular Angiography and Interventions (SCAI) and Canadian Association of Interventional Cardiology (CAIC) have formed the North American COVID-19 ST-Segment Elevation Myocardial Infarction Registry (NACMI). The study will be chaired by Tim Henry (SCAI) and Payam Dehghani...
A press release reports that the British Heart Foundation (BHF) and the National Institute of Health research (NIHR) have joined forces to launch a nationwide research initiative to better understand why people with heart and circulatory diseases are at...
VisCardia has been granted Breakthrough Device Designation from the US Food and Drug Administration (FDA) for its implantable VisONE system, which is designed for the treatment of moderate-to-severe heart failure with reduced ejection fraction and preserved ventricular synchrony. A...
LivaNova has announced that several of its cardiopulmonary products are can now be used in the USA for extracorporeal membrane oxygenation (ECMO) therapy for more than six hours, per guidance issued by the US Food and Drug Administration (FDA)...
In the Journal of American College of Cardiology, Ehtisham Mahmud (University of California, San Diego, Sulpizio Cardiovascular Center, La Jolla, USA) and others outline, in a consensus statement, recommendations for managing acute myocardial infarction during the COVID-19 pandemic. The...
A press release reports that several of the world’s ventilator manufacturers have formed a Ventilator Training Alliance (VTA) and partnered with Allego to create a mobile app that frontline medical providers can use to access a centralised repository of...
New data suggest that a medical device that uses vitamin B2 and ultraviolet light for treating human blood products is effective against the virus that causes COVID-19. The study results, generated by Terumo BCT in collaboration with top researchers...
Pi-Cardia has closed a US$27 million round of financing, led by Sofinnova Partners. A press release reports that Pi-Cardia’s Leaflex catheter performs mechanical scoring of valve calcification, restoring leaflets’ mobility and improving valve haemodynamics. The Leaflex catheter is designed...
Proximo Medical has announced a partnership with Elucid Bioimaging, a developer of diagnostic image analysis software used to assist in the detection and treatment of myocardial infarction and stroke. A press release states that Elucid Bioimaging’s signature technology, vascuCAP,...
Studies have shown that robotic percutaneous coronary intervention (PCI) with the CorPath GRX System (Corindus, now part of Siemens Healthineers)—compared with manual PCI—reduces radiation exposure to the cath lab staff and may also improve precision. Furthermore, during the current...
In response to a recent American College of Cardiology (ACC) review that advocated that troponin should only be measured when a diagnosis of acute myocardial infarction is being considered, Andrew R Chapman (BHF Centre for Cardiovascular Science, Royal Infirmary...
In the first of a series of webinars focusing on COVID-19, Society for Cardiovascular Angiography and Interventions (SCAI) president Ehtisham Mahmud (Cardiovascular Medicine, University of California, La Jolla, USA) and colleagues reviewed transcatheter aortic valve implantation (TAVI) procedures during...
The COVID-19 pandemic is hitting the world hard. Egypt, the most populous country in the Middle East and North Africa (MENA) region, is no exception. With more than 2,500 confirmed cases and a preliminary case fatality rate of 7%...
Impulse Dynamics has announced the publication of the FIX-HF-5C2 study in Circulation: Heart Failure. A press release reports that the study affirms the safety and efficacy of the company’s 2-lead version of the Optimizer system, which was approved by...
Enrique Ostrzega (University of Southern California, Los Angeles, USA) and colleagues report in in JACC: Case Reports that using applied abdominal pressure relived the symptoms of an apparent sudden-onset ST-segment elevation myocardial infarction (STEMI) in a patient with severe...
The US Food and Drug Administration (FDA) issued an emergency use authorisation for a blood purification system (Spectra Optia Apheresis System, Terumo BCT) combined with Adsorption Cartridge (Marker Therapeutics) to treat patients 18 years of age or older with confirmed...
Santiago Garcia (Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital, Minneapolis, USA) and colleagues report in the Journal of the American College of Cardiology that there was a 38% drop in cath lab ST-segment elevation myocardial infarction (STEMI) activations in...
The American Heart Association (AHA) has compiled interim CPR guidelines to help rescuers treat cardiac arrest patients with suspected or confirmed COVID-19. The guidelines are in collaboration with the American Academy of Pediatrics, American Society of Anesthesiologists, American Association...
In a brief report in Annals of Internal Medicine, Seongman Bae (Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea) and colleagues report that neither surgical nor cotton masks appear to be an effective approach for preventing the dissemination of SARS-CoV-2 from...
Physicians recognised the importance of remote management for heart failure patients long before the COVID-19 pandemic. However, the current situation has heightened the urgency of the transition for this vulnerable population. In this commentary, Michael Kiernan reviews how remote...
In separate statements, the European Society of Cardiology (ESC) and American College of Cardiology (ACC) are calling for patients to still seek immediate medical attention if they experience symptoms of a myocardial infarction despite any fears they may have...
Abbott has received the CE mark for its TriClip transcatheter tricuspid valve repair system. It can, therefore, be used as a non-surgical treatment for people with a leaky tricuspid valve in Europe and in other regions where the CE...
Presidents of leading cardiac organisations, including the American Heart Association (AHA), the American College of Cardiology (ACC) and the Heart Rhythm Society (HRS), have published a statement that cautions against the use of hydroxychloroquine and azithromycin for the treatment...
Royal Philips has announced that the US government and Philips agreed to team up to increase the production of hospital ventilators in its manufacturing sites in the USA. Philips plans to double the production by May 2020  and achieve...
Mardil Medical has announced the successful completion of treatment for the third patient in the clinical trial of its improved VenTouch device for type IIIb functional mitral valve regurgitation. A press release reports that the device is a combination...
Shockwave Medical has completed enrolment in its US Food and Drug Administration (FDA) Investigational Device Exemption (IDE) study—DISRUPT CAD III—for the use of intravascular lithotripsy (IVL) for the management of heavily calcified coronary arteries. A press release reports that...
Ahmed Bendary describes the findings of a meta-analysis published last month that determined outcomes for cancer patients following transcatheter aortic valve implantation (TAVI). He tells Cardiovascular News what can be done to ensure that these patients survive valvular problems.  Patients...
A soft robotic heart that is designed to replace the need for a heart transplant is one of four research projects that have made the shortlist for the Big Beat Challenge initiative—organised by the British Heart Foundation—that awards £30m...
At the 2019 European Association of Cardio-Thoracic Surgeons (EACTS) annual meeting (3–5 October, Lisbon, Portual), Max Y Emmert (Institute for Regenerative Medicine, University of Zurich, Switzerland/the Department for Cardiothoracic and Vascular Surgery, German Heart Center Berlin and Charite Berlin,...
Cardiovascular specialists from across the globe shared current knowledge and key experience of managing COVID-19 patients as part of a webinar organised by the Imperial College Network of Excellence in Vascular Science at Imperial College London. The four-part COVID-19 Cardiovascular...
The American Heart Association (AHA), in conjunction with the American Association for Respiratory Care (AARC) and American Society of Anesthesiologists (ASA) is offering guidance in oxygenation and ventilation management for healthcare providers as hospital volumes surge from COVID-19. AHA released...
The reduced levels of angiotensin converting enzyme (ACE) 2 associated with cardiovascular disease and increasing age lead to a higher susceptibility to greater disease severity in COVID-19. A viewpoint published online in JAMA Cardiology hypothesises that severe acute respiratory...
Edwards Lifesciences has temporarily paused new enrolments in its active pivotal clinical trials of its transcatheter mitral and tricuspid therapies in response to ongoing COVID-19 pandemic. A press release reports that the company is coordinating closely with the trials’...
The European Commission (EC) has adopted a proposal to postpone by one year the date of application of the new Medical Devices Regulation (MDR), which was due to come into force on 26 May this year. The postponement, a press...
Athena Poppas (Providence, USA) is the new president of the American College of Cardiology (ACC). Her term officially began at the close of the ACC/World Congress of Cardiology’s virtual scientific sessions (ACC.20/WCC Virtual). Poppas has been a long-standing leader of...
Simon Ray, president of the British Cardiovascular Society (BCS), has told the COVID-19 Cardiovascular Conference that a lack of consistency in national guidance around personal protective equipment (PPE) during COVID-19 had led to a “vacuum” which has had to...
In a new statement published on 2 April 2020, all 45 societies represented by the US Council of Medical Specialty Societies (CMSS)—over 800,000 physicians—emphatically declare their belief that all frontline healthcare professionals must have access to personal protective equipment...
A raised troponin level in myocardial injury “greatly alters the prognosis adversely” in COVID-19 patients, Graham Cole (Imperial College Healthcare NHS Trust, London, UK) told a virtual cardiovascular conference, hosted today by Imperial College London. Cole explained: “Troponin rises occur...
The COVID-19 Cardiovascular Conference, hosted as a live webinar by The Imperial College Network of Excellence in Vascular Science at Imperial College (London, UK), has heard about experiences from both Italy and the USA, as well as details of...
Cardiologists from across Europe have shared their experience of having treated COVID-19 patients, in a series of videos produced by the European Society of Cardiology (ESC), part of a suite of resources provided by the society to aid physicians...
The American College of Surgeons (ACS) today leapt to the defense of healthcare workers who are heading to work in the face of increasing concerns over personal protective equipment (PPE) shortages as the COVID-19 pandemic cuts trails across the...
Daniel M Philbin Jr has been named chair of the American College of Cardiology (ACC) board of governors and secretary of the board of trustees, the main governing body of the ACC, for 2020–2021. His term began at the...
The Imperial College Network of Excellence in Vascular Science at Imperial College London (UK) is to run a COVID-19 Cardiovascular Conference as a live webinar on Thursday 2 April for all healthcare professionals battling COVID-19. The webinar aims to share...
According to Geu-Ru Hong (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea), edoxaban may be an alternative to warfarin for preventing thromboembolism in the first three months after surgical bioprosthetic valve replacement or repair....
Results from the phase 2 MAVERICK-HCM clinical trial, presented at the American College of Cardiology/World Congress of Cardiology’s virtual scientific sessions (ACC.20/WCC Virtual) suggest that the use of mavacamten (MyoKardia) for the treatment of non-obstructive hypertrophic cardiomyopathy (nHCM) may be...
The longest follow-up to date of patients with left main coronary artery disease (LMCAD) has found no significant differences in rates of death, myocardial infarction or stroke between patients who underwent percutaneous coronary intervention (PCI) and those who had...
Today at the American College of Cardiology/World Congress of Cardiology’s virtual scientific sessions (ACC.20/WCC Virtual)—originally scheduled to take place on 28–30 March in Chicago, USA—D Scott Lim (University of Virginia, Charlottesville, USA) reported that mitral regurgitation ≤1+ was achieved more frequently with MitraClipNTR or with MitraClipXTR (both Abbott) than...
Using the radial artery instead of the saphenous vein for patients undergoing coronary artery bypass graft (CABG) surgery leads to lower mortality and better cardiac outcomes, according to research presented at the American College of Cardiology’s Virtual Scientific Session...
Medtronic today announced positive results of the Onyx ONE Clear Study that evaluated the Resolute Onyx drug-eluting stent (DES) in high bleeding risk (HBR) patients with one-month dual antiplatelet therapy (DAPT) in the USA and Japan. Results from the...
“More bleeding with background clopidogrel, even if not severe by adjudication, may be associated with broad consequences, including discontinuation of therapies. In the absence of clear benefit, clopidogrel exposure along with aspirin and rivaroxaban should be minimised or avoided...
Transcatheter aortic valve implantation (TAVI) procedures had a high rate of success and low risk of death or disabling stroke at 30 days in patients with a bicuspid aortic valve, according to research presented by Basel Ramlawi (Valley Health,...
Three months after undergoing renal denervation, patients with untreated high blood pressure had statistically significant reductions in average blood pressure over 24 hours compared with patients who underwent a sham procedure according to results from the SPYRAL-HTN OFF MED pivotal...
Data from the National Cardiovascular Data Registry (NCDR) Left Atrial Appendage Occlusion (LAAO) Registry, which enrolled more than 38,000 patients implanted percutaneously with the Watchman device (Boston Scientific), reveal a high implant success rate and a low rate of...
In the POPULAR TAVI trial, patients with atrial fibrillation who took oral anticoagulants alone after undergoing transcatheter aortic valve replacement (TAVI)—had a lower rate of bleeding complications without an increased risk of clotting-related complications, compared to patients who took...
During the first Featured Clinical Research session of the virtual American College of Cardiology (ACC) event (28–30 March, Central Time), Michelle Samuel (Montreal Health Institute, Montreal, Canada) reported that the addition of low-dose colchicine (0.5mg daily) to standard-of-care therapy...
In stable atherosclerosis, a combination of aspirin plus rivaroxaban provided a similar relative degree of benefit on coronary, cerebrovascular, and peripheral endpoints in patients with and without diabetes, a prespecified analysis of the COMPASS trial has shown. It also...
Treatment with aspirin plus rivaroxaban following lower extremity revascularisation in patients with peripheral arterial disease (PAD) leads to a 15% reduction in the risk of major adverse limb and cardiovascular events when compared with aspirin alone. The VOYAGER PAD study...
Today, during the Virtual American College of Cardiology (ACC) event (28–30 March, Central Time), Naveen L Pereira (Mayo Clinic, Rochester, USA) told the online audience that using genetic testing to guide antiplatelet therapy after percutaneous coronary intervention (PCI) does...
During a Q&A section of a European Commission (EC) college meeting on 25 March, EC spokesperson Stefan de Keersmaecker stated that the commission were looking to delay the “entry into force” of the new European medical device regulations (MDR) because of...
A viewpoint in the Journal of the American Medical Association (JAMA) has offered potential solutions to modifying ongoing randomised clinical trials during the COVID-19 pandemic. It aims to “minimise disruption and preserve integrity”, while still ensuring participant health and...
Cardiac injury is common among hospitalised patients with COVID-19, and is associated with a higher risk of in-hospital mortality, a study from Wuhan, China, has shown. Although the exact mechanism of cardiac injury has not been defined, the researchers...
The US Food and Drug Administration’s (FDA) Center for Devices and Radiological Health (CDRH) has written to the medical device industry to outline its response to the COVID-19 public health emergency in its day-to-day operations with industry. The letter from...
The American Heart Association (AHA) has committed US$2.5 million to research efforts to better understand the novel coronavirus, COVID-19, and its interaction with the body’s cardiovascular and cerebrovascular systems. Specifically, the Association will be offering fast-tracked research grants for short-term...
The British Cardiovascular Intervention Society (BCIS) and the British Cardiovascular Society (BCS) have endorsed guidance published by NHS England and NHS Improvement on the provision of cardiology services during the COVID-19 pandemic. A joint statement from Nick Curzen, president of...
The Society for Cardiology and Angiography Interventions (SCAI) has set up a dedicated section on its website to keep interventional cardiologists up to date on practice and safety measures required for interventional practice in COVID-19. The society has also...
CroíValve has announced the successful first human use of its Duo Tricuspid Coaptation Valve technology for tricuspid repair. The company says the procedure was performed by an experienced heart team in St James’ University Hospital (Dublin, Ireland). A statement from...
A new Heart & Stroke guideline published today in the Canadian Medical Association Journal does not recommend taking ASA (Acetylsalicylic acid) as a preventive measure for those who do not have a history of stroke or heart or vascular disease,...
A case series of US experience with COVID-19 has upheld suggestions of a link with cardiomyopathy, which developed in 33% of intensive care patients. In a research letter published in the Journal of the American Medical Association, Matt Arentz (Department...
The US Food and Drug Administration (FDA) has issued an immediately-in-effect guidance that allows manufacturers of certain FDA-cleared non-invasive, vital-sign-measuring devices to expand their use so that health care providers can use them to monitor patients remotely. The devices...
The first report on the impact of COVID-19 on heart transplant recipients has been published in The Journal of Heart and Lung Transplantation, outlining the management strategy by a team in Wuhan for two patients who contracted the virus...
Frailty is an independent predictor of morbidity, death, and increased costs after mitral valve replacement (MVR), a retrospective cohort study has determined. Writing in The Annals of Thoracic Surgery, Amit Iyengar (Division of Cardiac Surgery, and Perelman School of Medicine,...
The Society for Cardiovascular Angiography and Interventions (SCAI) has written an open letter to members detailing options for managing patients in the cath lab who present with COVID-19. SCAI president Ehtisham Mahmud, (University of California, San Diego) points out: “A...
Data from a pilot imaging study of commissural alignment in trancatheter aortic valve implantation (TAVI) has found that more than 30–50% of cases had overlap with one or both coronary arteries. Gilbert HL Tang (Mount Sinai Medical Center, New...
European CE mark has been awarded to the TriGUARD 3 cerebral embolic protection (CEP) device from Keystone Heart, a Venus Medtech Company. According to the company, TriGUARD 3 is the only CE marked product designed to cover and protect all...
Portola Pharmaceuticals announced new data that they say reinforces the value of Andexxa (coagulation factor Xa , inactivated-zhzo]. The company statement outlines that the data demonstrate Andexxa was associated with a lower rate of in-hospital and 30-day mortality in...
Early improvement in health status for patients in the COAPT trial who had transcatheter mitral valve repair (TMVr) with the MitraClip (Abbott) was strongly associated with reduced long-term risk of death or heart failure hospitalisation. COAPT investigators Suzanne V Arnold...
Patients who have a percutaneous coronary intervention (PCI) for chronic total occlusion following a coronary artery bypass graft (CABG) have worse outcomes than those without prior surgery, a meta-analysis published in JACC: Cardiovascular Interventions has found. The research was...
The novel left atrial appendage (LAA) closure device Appligator (Append Medical) was a finalist in the 2019 ICI Innovation Award Competition (Innovation in Cardiovascular Interventions 2019; 8–10 December, Tel Aviv, Israel).  Leonid Sternik, who came up with the concept...
Abbott made history in January when it became the first company in the world to receive market approval for a transcatheter mitral valve implantation (TMVI) device. Its Tendyne system now has a CE-mark indication for the management of patients...
The American College of Cardiology Scientific Session Together with World Congress of Cardiology (ACC.20/WCC) is to run as a virtual meeting, following its cancellation due to the coronavirus outbreak. It was scheduled to take place 28–30 March 2020 in...
Vascular remodelling may occur in response to sustained, regular exercise, suggests a study of aortic dilatation among long-term endurance athletes. Timothy W Churchill (Massachusetts General Hospital, Boston, USA) et al found a “marked increase in the prevalence of aortic...
Abbott has received CE mark in Europe for the new FlexNav delivery system for the company's Portico transcatheter aortic valve implantation (TAVI) system. A statement from the company says that with the approval, physicians implanting Portico can benefit from...
The New England Journal of Medicine (NEJM) has launched a review into the data from the EXCEL trial, two members of the BBC Newsnight team have reported in the BMJ. Deborah Cohen and Ed Brown from the Newsnight current...
A short film (“Today is a Good Day”), which showcases the work of Aortic Dissection Awareness UK & Ireland, has won the Rare Disease Film Festival’s Peoples’ Choice award. According to Rare Disease UK, the organisers of the event, the film festival...
NOTE: This video is ONLY available to watch in selected countries and geographies Rajesh Kharbanda (Oxford, UK) and Oliver Husser (Dortmund, Germany) talk to BLearning Cardio about some of the major advancements in TAVI procedures over the past few years as well...
NOBLE finds PCI inferior to CABG at five years in left main disease EXCEL: repeat revascularisation after both CABG and PCI leads to increased mortality Profile: Nicolas van Mieghem BIBA Briefings: Sapien 3 becomes first TAVI valve to...
NOBLE finds PCI inferior to CABG at five years in left main disease EXCEL: repeat revascularisation after both CABG and PCI leads to increased mortality Profile: Nicolas van Mieghem BIBA Briefings: Sapien 3 becomes first TAVI valve to...
Paclitaxel drug coated balloons (DCB) for percutaneous treatment of coronary artery disease (CAD) are not associated with increased mortality, and longer term evaluation suggests a trend towards lower mortality compared to control therapies. The authors of a meta-analysis of...
Findings from an interim analysis of PROTECT III have added to the evidence for improved outcomes with Impella heart pumps in protected percutaneous coronary intervention (PCI). PROTECT III is part of the PROTECT series of trials initiated by Abiomed...
CryoLife has received CE mark for the On-X Ascending Aortic Prosthesis (AAP), allowing resumed distribution in the European Union. The On-X AAP is indicated for the treatment of diseased, damaged or malfunctioning native or prosthetic heart valves in the aortic...
The US Food and Drug Administration (FDA) has cleared a new version of the LivaNova Heater-Cooler System 3T, which is used during cardiothoracic surgery to warm or cool a patient to improve medical care and patient outcomes. The changes—designed,...
Endotronix has announced the enrollment of the first two patients in the PROACTIVE-HF trial. The trial is a premarket investigational device exempt (IDE) study evaluating the safety and efficacy of the Cordella pulmonary artery pressure sensor system (Cordella sensor)...
A research project at the University of Leeds aiming to identify new drug treatments for heart failure patients has been awarded a grant of almost £150,000 by British charity Heart Research UK.  The project, which will be led by Scott...
Transcatheter aortic valve implantation (TAVI) is safe in the short term in low-risk patients with symptomatic, severe bicuspid aortic stenosis (AS). Researchers also noted that subclinical leaflet thrombosis was present in a minority of patients at 30 days, but...
Patients who develop stage 3 acute kidney injury (AKI) following transcatheter aortic valve implantation (TAVI) have seven times higher adjusted one-year mortality than patients who do not develop AKI. Researchers also found that more than 10% of patients develop...
Biotronik has announced three-year data from the BIOFLOW-V trial, which were presented at the Cardiac Resynchronisation Therapy meeting (CRT 2020; 23–25 February, Washington DC, USA). A statement from the company says the three-year findings demonstrate consistently lower clinical event...
Append Medical, developer of the Appligator, a novel left atrial appendage (LAA) closure device to minimise stroke risk in atrial fibrillation (AF) patients, and Sheba Medical Center (Ramat Gan, Israel), have announced the clinical proof-of-concept data evaluating the safety...
Edwards Lifesciences has announced a new goal for its philanthropic initiative, Every Heartbeat Matters (EHM), which aims to improve the lives of 2.5 million additional underserved structural heart and critical care patients by the end of 2025. The company...
A comparison of newer generation self-expanding valves (SEV) and balloon-expandable valves (BEV) in high-risk patients with aortic stenosis undergoing transfemoral transcatheter aortic valve implantation (TAVI) has found that they are equivalent for the primary valve-related efficacy endpoint. The authors...
Ablative Solutions has revealed that positive six-month results from the Peregrine post-market study demonstrating the safety and efficacy of the company’s CE-marked Peregrine System infusion catheter were published in the Journal of the American College of Cardiology: Cardiovascular Interventions. The...
Cardiovalve has received US Food and Drug Administration (FDA) approval for an early feasibility study (EFS) of its transcatheter tricuspid valve replacement system for a tricuspid regurgitation (TR) indication. The Cardiovalve System has also been granted Breakthrough Device Designation...
Last month, Abbott announced US Food and Drug Administration (FDA) approval of a new trial—REPAIR MR—to evaluate the safety and efficacy of percutaneous edge-to-edge repair (MitraClip) for the management of patients with primary mitral regurgitation at moderate surgical risk....
The news programme BBC Newsnight has made further claims that the EXCEL investigators “held back” data from the published results of the left main trial. In a programme that aired on 18 February, reporter Deborah Cohen claims that Gregg...
VitalConnect has announced the introduction of arrhythmia detection to its remote monitoring portfolio. In partnership with CorVitals, VitalConnect now offers physicians the ability to monitor, diagnose and treat patients suffering from various heart conditions and diseases. With arrhythmia detection, clinicians...
Gregg W Stone (Icahn School of Medicine, Mount Sinai, New York, USA) addressed the EXCEL controversy today at the Joint Interventional Meeting (JIM 2020; 13–15 February, Milan, Italy), stipulating that although percutaneous coronary intervention (PCI) has early advantages and...
Nicolas van Mieghem

Nicolas van Mieghem

Nicolas van Mieghem (professor of interventional cardiology, department of cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the Netherlands) shares his thoughts on a wide range of topics with Cardiovascular News, including mechanical circulatory support and artificial intelligence, the durability...
The US Food and Drug Administration (FDA) has authorised marketing of software to assist in the acquisition of cardiac ultrasound, or echocardiography, images. The software, called Caption Guidance (Caption Health), is an accessory to compatible diagnostic ultrasound systems and...
Orsiro Mission DES

Orsiro Mission gets CE mark

Biotronik has received CE mark certification for the Orsiro Mission drug-eluting stent (DES) system. According to a company statement, the next generation of the ultrathin strut Orsiro DES provides higher deliverability than other contemporary stents. Orsiro Mission is now...
Philips has announced a new randomised controlled trial to assess percutaneous coronary intervention (PCI) guided by its coregistration platform, which combines data of an instant wave-Free Ratio (iFR) measurement and an angiogram, compared with standard of care treatment guided...
Scott Lim (Charlottesville, USA) talks to BLearning Cardio at PCR London Valves 2019 (17–19 November, 2019; London, UK) about the challenges associated with transcatheter tricuspid valve intervention. Lim explains that the patient population with tricuspid regurgitation is very heterogeneous, and so there is a need for a...
 Philippe Pibarot (Québec, Canada) talks to BLearning Cardio at PCR London Valves 2019 (17–19 November, 2019; London, UK) about the main data findings in the PARTNER 2 trial which evaluated more than 2,000 intermediate-risk patients with severe aortic stenosis who either underwent a TAVI procedure...
BioVentrix has received renewal of the highest priority reimbursement in Germany for its Revivent TC transcatheter ventricular enhancement system. A company statement announced that it has been given NUB Status 1 designation from InEk, the German Institute for Hospital...
Extended 10-year follow-up has demonstrated that in patients with a high SYNTAX score undergoing left main coronary artery (LMCA) revascularisation there is a clear prognostic benefit for coronary artery bypass graft (CABG) over percutaneous coronary intervention (PCI). PCI was...
The debate over the results of EXCEL shows no sign of abating, and there seems to be a division between cardiac surgeons and interventional cardiologists about which side of the argument they fall on, with surgeons generally supporting EACTS,...
Medtronic has announced that it will begin enrolment in a pilot study evaluating the safety and efficacy of the Symplicity Spyral renal denervation (RDN) system using a targeted procedural approach with a reduced number of radio frequency (RF) ablations....
The US Food and Drug Administration (FDA) has granted Breakthrough Device Designation to Abbott for its in-development fully implantable left ventricular assist system (FILVAS). The FDA Breakthrough Device Designation programme will allow, according to Robert L Kormos (medical director...
Rajiv Patni has been appointed as executive vice president and chief medical officer at Portola Pharmaceuticals, effective immediately. The company announced the appointment in a press release, stating that Patni will report to Scott Garland, president and chief executive...
 Frank Arko (Charlotte, USA) talks to VEITHtv at the VEITHsymposium 2019 (19–23 November, New York, USA), about the benefits of using Shockwave Intravascular Lithotripsy (IVL) when performing EVAR and TEVAR through calcified iliac arteries. Arko, who shares some of the downsides of traditional procedures...
Guy’s and St Thomas’ and Royal Brompton & Harefield NHS Foundation Trusts are to merge. A joint statement from the two trusts has announced their plans for closer working, indicating that the arrangements include the creation of a hub...
The Tendyne transcatheter mitral valve implantation (TMVI) system (Abbott) has received the CE mark, making Abbott the first company to have such a device on a market anywhere in the world. A press release reports that this “life-changing” therapy...
Highly-tweeted articles are 11 times more likely to be cited than less tweeted articles, Ourania Preventza (Division of Cardiothoracic Surgery, Baylor College of Medicine, Houston, USA) told delegates at the 56th Annual Meeting of The Society of Thoracic Surgeons...
David Hayes, former physician administrator at Mayo Clinic, Rochester, USA, has been appointed chief medical officer of Biotronik, a company press release reports. "Our focus has always been on the patient. To help patients live their best lives, we remain...
Open heart surgery remains the best option for young and middle-aged adults with aortic valve disease, for now; However, the use of transcatheter aortic valve implantation (TAVI) is continuing to expand to a wider group of eligible patients, according...
Patients discharged three days after open heart surgery are not at increased risk of complications, an analysis of discharge patterns has shown. S Chris Malaisrie (Northwestern Medicine, Chicago, USA) unveiled the findings at the 56th Annual Meeting of the Society...
NOTE: This video is ONLY available to watch in selected countries and geographies Azeem Latib (New York, USA) talks to BLearning Cardio about some of the major advancements in TAVI over the past few years including the...
Terumo has announced the launch of a new randomised clinical trial: the DIStal vs. COnventional RADIAL access trial (DISCO RADIAL). The trial compares the novel distal radial access with conventional radial access approach, in terms of radial occlusion rates...
The largest study to date of the role of frailty indices after transcatheter aortic valve implantation (TAVI) has demonstrated that the markers of low albumin, anaemia, and slow walking speed are significant independent predictors of mortality and morbidity in...
The TASTE and TOTAL studies suggested that routine thombus aspiration in patients undergoing percutaneous coronary intervention (PCI) did not provide mortality benefit and may increase the risk of stroke. However, a new study (CHEETAH) is evaluating whether a next-generation...
FEops has announced that the first patient has been enrolled in the physician-initiated PREDICT-LAA trial. The trial is led by Righshospitalet (Copenhagen, Denmark) and aims to assess whether the use of FEops HEARTguide computer simulations based on cardiac CTimaging can...
George Adams (Raleigh, USA) talks to VEITHtv at the VEITHsymposium 2019 (19–23 November, New York, USA) about the benefits of using easy-to-use Shockwave IVL (Intravascular Lithotripsy) in calcified below-the-knee vessels, which he says, results in “great outcomes”. Adams explains that calcific plaque, particularly medial...
Emboline has completed enrolment in its SAFEPASS 2 clinical study of the Emboliner embolic protection catheter. A press release from the company, which develops total embolic protection technology for transcatheter aortic valve implantation (TAVI), also indicates that early results...
BioCardia has received US Food and Drug Administration (FDA) 510(k) clearance for its Morph DNA deflectable guide catheter, used to guide the Helix biotherapeutic delivery system during CardiAMP cell therapy delivery in the heart. A company statement explains that the...
Spartan Bioscience, a maker of precision medicine diagnostic solutions, has established a new scientific advisory board (SAB) in Europe for cardiac stent patients that consists of international clinical and academic interventional cardiologists. The company says the role of the...
A secondary analysis of repeat revascularisation in the EXCEL trial has found that it was associated with increased mortality after both percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) in patients with left main coronary artery disease...
The Society of Thoracic Surgeons (STS) has issued a statement on the controversy surrounding EXCEL, commenting that “that the final interpretation regarding the outcomes of the EXCEL study should wait until an independent analysis of all aspects of the...
The American College of Cardiology (ACC) has announced several promotions and structural changes within its senior staff. The College said that the staff changes will “further consolidate and strengthen the organisation’s efforts in achieving its strategic goals, mission and...
Abbott has announced that the US Food and Drug Administration (FDA) has approved a first-of-its-kind clinical trial that will compare the effectiveness of Abbott's MitraClip device to open heart mitral valve surgical repair in people with primary mitral regurgitation...
A retrospective registry comparing four self-expanding transcatheter heart valves has demonstrated good haemodynamic performance in small aortic annuli, with low post-procedure gradients, large orifice areas, and a low incidence of severe patient–prosthetic mismatch (PPM). Writing in JACC: Cardiovascular Interventions, investigators...
Abbott has announced US Food and Drug Administration (FDA) approval of a new alternative surgical technique for Abbott's HeartMate 3 heart pump that the company says will allow more advanced heart failure patients to avoid open heart surgery. The...
B Braun has announced the appointment of Jean-Claude Dubacher as chairman and CEO. Dubacher joined B Braun on 1 August 2019 as president, B Braun Medical. A press release reports that Dubacher’s experience in the healthcare industry spans more...
Proximo Medical is to partner with CeloNova Biosciences, supplier of the COBRA PzF nanocoated coronary stent (NCS), in select US markets. Carl St Bernard, chief executive officer of CeloNova Biosciences, states in the press release: “By partnering with Proximo Medical,...
The European Association of Cardio-Thoracic Surgeons (EACTS) has issued a statement reaching out to EXCEL investigators to “offer assistance” in resolving concerns raised about data from the trial. In a letter sent to the principal investigators, EACTS recommends that...
The European Association of Cardio-Thoracic Surgeons (EACTS) has published a detailed account of the process that led to its “unprecedented” decision to reverse its endorsement of a section of its joint 2018 myocardial revascularisation guidelines, developed with the European...
Five-year data from the NOBLE trial have confirmed its earlier findings that in patients with unprotected left main coronary disease the risk of major adverse cardiac or cerebrovascular events (MACCE) is higher with percutaneous coronary intervention (PCI) than with...
The Society for Thoracic Surgeons (STS) and the European Association of Cardio-Thoracic Surgeons (EACTS) have announced that they will participate in a strategic collaboration. A joint press release issued by Robert SD Higgins, president of the STS, and Domenico Pagano,...
The US Food and Drug Administration has granted Breakthrough Device designation to the digital health and artificial intelligence (AI) company Eko for an echocardiogram (ECG)-based algorithm to help identify induced Left Ventricular Ejection Fraction (LVEF). FDA Breakthrough Device designation helps...
Daiichi Sankyo Europe has announced outcomes from an observational study in mainly caucasian atrial fibrillation (AF) patients being treated with the anti-coagulation drug edoxaban (Lixiana). The results of the Danish observational cohort study, published in the European Heart Journal...
A pivotal, multicentre clinical trial is exploring the use of an Impella heart pump (Abiomed) to unload the left ventricle for 30 minutes prior to coronary revascularisation. The aim of the trial is to test the hypothesis that unloading...
Edwards Lifesciences has received the CE mark for its Sapien 3 transcatheter aortic valve implantation (TAVI) device to be used to manage aortic stenosis in low-risk patients. Both Edwards and Medtronic (with its CoreValve Evolut range) have FDA approval...
Gregg Stone (The Zena and Michael A Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, USA), on behalf of the EXCEL leadership, has sent Cardiovascular News (and other media outlets) a 3,500-word document refuting the...
George Dangas (Mount Sinai Hospital, New York, USA) told delegates in a late-breaking trial session at the American Heart Association Scientific Sessions (AHA 2019; 16–18 November, Philadelphia, USA) that “in patients without an established indication for oral anticoagulation after...
  The European Association of Cardio-Thoracic Surgery (EACTS) has withdrawn its support of the left main recommendations of the society’s joint guidelines with the European Society of Cardiology (ESC) on myocardial revascularisation following an investigation into the EXCEL trial by the...
InnovHeart—a developer of novel transcatheter mitral valve replacement (TMVR) systems—has appointed medical device entrepreneur J Brent Ratz as nonexecutive independent member of its Board of Directors. A press release reports that Ratz has more than 19 years of experience...
Data from the CAP and CAP2 registries—which contain the longest and largest follow-up of patients—add to previous evidence that left atrial appendage closure (LAAC) with Watchman (Boston Scientific) is a safe and effective alternative to long-term anticoagulation in patients...
Bioventrix has announced online publication of positive one-year results from its CE mark study of the Revivent TC System in the European Journal of Heart Failure. The paper will be published in print in the January issue. A press statement...
The TASTE and TOTAL studies suggested that routine thombus aspiration in patients undergoing percutaneous coronary intervention (PCI) did not provide mortality benefit and may increase the risk of stroke. However, a new study (CHEETAH) is evaluating whether a next-generation...
  A significant milestone has been reached for a landmark study into the use of short duration dual anti-platelet therapy (DAPT) in high-bleeding-risk (HBR) patients following stenting procedures, with patient recruitment just completed. A total cohort of approximately 4,500 patients have...
Michael Reardon (Houston, USA) talks to BLearning Cardio about the ADAPT tissue technology (Admedus), and the increasing importance of durability as TAVI moves to younger and lower risk patients. Reardon notes that “we would like to have technology that does even better...
The largest trial to date to compare revascularisation with a conservative strategy in patients with stable ischaemic heart disease has found no additional benefit a median of three years after the procedure. Data from the ISCHEMIA trial were presented at...
Preprocedural administration of an oral colchicine load does not reduce the risk of myocardial injury or 30-day major adverse cardiovascular events (MACE) in patients undergoing percutaneous coronary intervention (PCI), according to findings from the COLCHICINE-PCI (Effects of acute colchicine...
Meril has announced positive data on its Myval Transcatheter Heart Valve System at PCR London Valves 2019 (17–19 November 2019). A follow-up of 100 patients with intermediate- to high-risk for surgical aortic valve replacement (SAVR) in the MyVal-1 study...
Corindus has announced the completion of the first multicity, transcontinental percutaneous coronary intervention (PCI) simulations in the USA over three network connection types: 5G wireless, dedicated fibre, and commercial public internet networks. A press release reports that Ryan Madder...
The Revivent transcatheter ventricular enhancement system (Bioventrix) has been granted Breakthrough Device Designation by the US Food and Drug Administration (FDA). The Revivent investigational transcatheter device uses micro-anchors to cinch together the scarred area of the left ventricle to...
An analysis of structural valve deterioration in the PARTNER 2A trial has found that the third generation Sapien 3 transcatheter heart valve (Edwards Lifesciences) has similar durability to surgical valves, with the second generation Sapien XT (also Edwards Lifesciences)...
The use of TriClip (Abbott) for edge-to-edge repair in tricuspid regurgitation (TR) remains safe and effective at one year, preliminary outcomes from the TRILUMINATE study, presented at a late-breaking session at PCR London Valves 2019 (17–19 November, London, UK),...
Permanent pacemaker implantation (PPI) after transcatheter aortic valve implantation (TAVI) is associated with increased mortality at six years, particularly in patients who are pacemaker dependent. At an abstract session at PCR London Valves 2019 (17–19 November, London, UK), Giuliano...
Endotronix has presented first-in-human data of the Cordella pulmonary artery pressure sensor System at the 2019 American Heart Association (AHA) Scientific Sessions (16–18 November, Philadelphia, USA). Data were presented by Wilfried Mullens (Hospital Oost-Limburg, Genk, Belgium). The 90-day results from...
A single-centre real world experience has found that the vast majority of patients with severe mitral regurgitation (MR) were not eligible for inclusion in the COAPT trial, with the most frequent reason for exclusion being that they were not...
Over the past few years, the indications for transcatheter aortic valve implantation (TAVI) have expanded from inoperable patients to low-risk patients—meaning that TAVI can now be considered for all aortic stenosis patients, regardless of their surgical risk.1 However, using...
The mortality risk for patients with critical limb ischaemia (CLI) has not changed over the last few decades, despite advances in cardiovascular medicine that treat myocardial infarction and stroke, the two biggest causes of death in these patients, Sahil...
Shockwave Medical has initiated the DISRUPT CAD IV study of its intravascular lithotripsy (IVL) system with the aim of using data from the study to support regulatory device approval in Japan. The system is used in the management of...
A wrist-based optical blood pressure monitor has the potential to replace cuff monitoring systems for ambulatory blood pressure, suggests a study in the journal Blood Pressure Monitoring. A press release from Aktiia, the Swiss-based company manufacturing the device, states...
The use of multiphase computed tomography (CT) assessment, particularly during the early systolic phase, of the neo-left ventricular outflow tract (LVOT) is a better predictor of clinically relevant obstruction in transcatheter mitral valve replacement (TMVR) than end systole measurements....
A prespecified subgroup analysis of the GLOBAL LEADERS trial has found no between-sex difference in the risk of two-year all-cause mortality or new Q-wave myocardial infarction (MI) following percutaneous coronary intervention (PCI). Published online in JAMA Cardiology, the study...
Left atrial appendage closure (LAAC) via implanted device was associated with a decreased risk of admission for stroke, compared with the expected risk without anticoagulation therapy, according to a study published in the Journal of the American Medical Association...

Ehtisham Mahmud

The 2019–20 president of the Society for Cardiovascular Angiography and Interventions (SCAI) Ehtisham Mahmud (division chief, Cardiovascular Medicine, UC San Diego, San Diego, USA) tells Cardiovascular News about his career highlights, and outlines the key priorities for his presidency. 1....
Patients who have mixed aortic valve disease with pre-existing aortic regurgitation have better survival rates following transcatheter aortic valve implantation (TAVI) than those who have aortic stenosis alone. Writing in JACC: Cardiovascular Interventions, Johnny Chahine (Cleveland Clinic, Cleveland, USA)...
CorFlow Therapeutics has announced that the company has been granted Breakthrough Device designation from the US Food and Drug Administration (FDA) for its Controlled Flow Infusion (CoFI) System. It is indicated for the diagnostic assessment of the coronary microcirculation...
Cardionovum's Restore paclitaxel-coated balloon for coronary applications has received market approval for use in China. It can be used in treating two indications: in-stent restenosis and small vessel disease. A joint press release from Cardionovum and China Grand Pharmaceutical...
The stockholders of Corindus Vascular Robotics have approved the adoption of the agreement and plan of merger that was drawn up in August by Siemens Medical Solutions USA (Siemens Healthineers), Corpus Merger, and Corindus. A press statement reports that...
Further evidence for a shorter duration of dual antiplatelet therapy (DAPT) in patients implanted with a drug eluting stent has been provided with the presentation of two studies at Transcatheter Cardiovascular Therapeutics (TCT 2019; 24–29 September, San Francisco, USA). Data...
Using optical coherence tomography (OCT)-to guide percutaneous coronary intervention (PCI) is associated with a lower occurrence of major adverse cardiac events (MACE) or significant angina in patients with angiographically-intermediate coronary lesions (AICL) than fractional flow reserve (FFR)-guidance. However, FFR...
Different strategies are needed to address the continuing lack of diversity in the US cardiology workforce, say the authors of a cross-sectional study which found that numbers of underrepresented minority individuals and women remain proportionately lower, and that progress...
A study published as a research letter in JAMA Internal Network has found a “substantial misclassification” of patient deaths for the Sapien 3 and MitraClip devices in the US Food and Drug Administration (FDA) database which, the authors say,...