Angela O'Neill

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Routine anticoagulation with rivaroxaban after TAVI harmful: GALILEO trial results

George Dangas (Mount Sinai Hospital, New York, USA) told delegates in a late-breaking trial session at the American Heart Association Scientific Sessions (AHA 2019;...

InnovHeart appoints Brent Ratz as independent member of the board

InnovHeart—a developer of novel transcatheter mitral valve replacement (TMVR) systems—has appointed medical device entrepreneur J Brent Ratz as nonexecutive independent member of its Board...

Bioventrix announces positive one-year outcomes for Revivent TC system

Bioventrix has announced online publication of positive one-year results from its CE mark study of the Revivent TC System in the European Journal of...

Further innovation and research is required for thrombus aspiration in PCI

The TASTE and TOTAL studies suggested that routine thombus aspiration in patients undergoing percutaneous coronary intervention (PCI) did not provide mortality benefit and may...

AHA 2019: ISCHEMIA shows no benefit for revascularisation in patients with...

The largest trial to date to compare revascularisation with a conservative strategy in patients with stable ischaemic heart disease has found no additional benefit...

AHA 2019: Preprocedural COLCHICINE-PCI finds a lowering of inflammation, but no...

Preprocedural administration of an oral colchicine load does not reduce the risk of myocardial injury or 30-day major adverse cardiovascular events (MACE) in patients...

PCR London Valves 2019: Meril unveils positive data for Myval

Meril has announced positive data on its Myval Transcatheter Heart Valve System at PCR London Valves 2019 (17–19 November 2019). A follow-up of 100...

Corindus completes first transcontinental simulated telerobotic PCI procedures over 5G, fibre,...

Corindus has announced the completion of the first multicity, transcontinental percutaneous coronary intervention (PCI) simulations in the USA over three network connection types: 5G...

Revivent transcatheter system receives Breakthrough Device Designation from the FDA

The Revivent transcatheter ventricular enhancement system (Bioventrix) has been granted Breakthrough Device Designation by the US Food and Drug Administration (FDA). The Revivent investigational...

PCR London Valves 2019: PARTNER 2 analysis shows Sapien 3 valve...

An analysis of structural valve deterioration in the PARTNER 2A trial has found that the third generation Sapien 3 transcatheter heart valve (Edwards Lifesciences)...

PCR London Valves 2019: TRILUMINATE shows safety and efficacy of TriClip...

The use of TriClip (Abbott) for edge-to-edge repair in tricuspid regurgitation (TR) remains safe and effective at one year, preliminary outcomes from the TRILUMINATE...

PCR London Valves 2019: A simple algorithm can reduce unnecessary pacemaker...

Permanent pacemaker implantation (PPI) after transcatheter aortic valve implantation (TAVI) is associated with increased mortality at six years, particularly in patients who are pacemaker...

PCR London Valves 2019: One-year survival better with Mitra Clip than...

A single-centre real world experience has found that the vast majority of patients with severe mitral regurgitation (MR) were not eligible for inclusion in...

More focus needed on best medical therapy and perfusion imaging for...

The mortality risk for patients with critical limb ischaemia (CLI) has not changed over the last few decades, despite advances in cardiovascular medicine that...

Shockwave commences IVL study to support regulatory approval in Japan

Shockwave Medical has initiated the DISRUPT CAD IV study of its intravascular lithotripsy (IVL) system with the aim of using data from the study...

“Cuffless” system to monitor blood pressure could replace traditional methods

A wrist-based optical blood pressure monitor has the potential to replace cuff monitoring systems for ambulatory blood pressure, suggests a study in the journal...

Multiphase and early systolic phase CT screening in TMVR superior to...

The use of multiphase computed tomography (CT) assessment, particularly during the early systolic phase, of the neo-left ventricular outflow tract (LVOT) is a better...

GLOBAL LEADERS: no sex-difference in mortality or MI rates two years...

A prespecified subgroup analysis of the GLOBAL LEADERS trial has found no between-sex difference in the risk of two-year all-cause mortality or new Q-wave...

Ehtisham Mahmud

The 2019–20 president of the Society for Cardiovascular Angiography and Interventions (SCAI) Ehtisham Mahmud (division chief, Cardiovascular Medicine, UC San Diego, San Diego, USA)...

Pre-TAVI aortic regurgitation aids survival post-TAVI in mixed aortic valve disease...

Patients who have mixed aortic valve disease with pre-existing aortic regurgitation have better survival rates following transcatheter aortic valve implantation (TAVI) than those who...

US FDA grants Breakthrough Device designation to CorFlow Infusion System

CorFlow Therapeutics has announced that the company has been granted Breakthrough Device designation from the US Food and Drug Administration (FDA) for its Controlled...

Cardionovum’s coronary DCB receives regulatory approval in China

Cardionovum's Restore paclitaxel-coated balloon for coronary applications has received market approval for use in China. It can be used in treating two indications: in-stent...

Corindus’ stockholders approve acquisition by Siemens Healthineers

The stockholders of Corindus Vascular Robotics have approved the adoption of the agreement and plan of merger that was drawn up in August by Siemens...

Two further studies support three-month DAPT following PCI

Further evidence for a shorter duration of dual antiplatelet therapy (DAPT) in patients implanted with a drug eluting stent has been provided with the...

In patients with angiographically-intermediate coronary lesions, OCT-guidance provides promising clinical results...

Using optical coherence tomography (OCT)-to guide percutaneous coronary intervention (PCI) is associated with a lower occurrence of major adverse cardiac events (MACE) or significant...

Diversity strategies in cardiology are not working, study finds

Different strategies are needed to address the continuing lack of diversity in the US cardiology workforce, say the authors of a cross-sectional study which...

Device deaths are under reported, says research letter

A study published as a research letter in JAMA Internal Network has found a “substantial misclassification” of patient deaths for the Sapien 3 and...

Shockwave study demonstrates strong safety and procedural success of coronary IVL...

Shockwave Medical, a company which provides intravascular lithotripsy (IVL) to treat complex calcified cardiovascular disease, unveiled the results of the DISRUPT CAD II study,...

International medical graduates in US cardiovascular care are vital to healthcare...

William W Pinsky and Mandeep R Mehra explain to Cardiovascular News how international medical graduates contribute to both their adopted country and their country...

Admedus sells CardioCel and VacsuCel to focus on TAVI

Admedus has sold the distribution rights to its CardioCel and VascuCel product range for $A36.2 million to US-based LeMaitre Vascular. A press release from...

Penumbra announces enrolment of first patient in study of mechanical power...

Penumbra has announced the enrolment of the first patient into the CHEETAH study, a prospective, multicentre US study to evaluate the safety and performance...

Douglas Drachman named as next vice chair of American College of...

Douglas Drachman has been selected as the next vice chair of the American College of Cardiology’s Annual Scientific Session. Drachman will serve as vice...

Abiomed announces PROTECT III clinical data for protected PCI with Impella

Abiomed has announced the results of PROTECT III, an ongoing, prospective, single-arm US Food and Drug Administration (FDA) post-market approval (PMA) study for Impella...

AccuCinch ventricular repair system associated with favourable safety profile at 30...

Data from an interim analysis of heart failure patients treated in the CorCinch FMR study show, a press release reports, that the AccuCinch ventricular...

TCT 2019: Apixaban plus a P2Y12 inhibitor is the optimal strategy...

A prespecified analysis of data from the AUGUSTUS study, released at late-breaking session at the Transcatheter Cardiovascular Therapeutics scientific symposium (TCT 2019; 25–29 September,...

CE mark granted to the Gore Cardioform ASD Occluder for the...

The Gore Cardioform Occluder for atrial septal defects (ASD) has received CE mark in Europe, the company has announced, stating that the move was...

Transseptal puncture techniques must be mastered if physicians wish to perform...

Interest in transseptal puncture has surged with the development of structural interventions for the left side of the heart. Francesco Maisano provides an update...

Endotronix closes expanded series D financing round of US$70 million for...

Endotronix has announced the expansion of its series D financing round, bringing the total to US$70 million. The expansion syndicate includes new investment from...

TCT 2019: Resolute Onyx noninferior to BioFreedom in high bleeding risk...

ONYX ONE, the first randomised trial to compare a durable polymer drug-eluting stent to a polymer-free drug-coated stent in patients at high risk of...

TCT 2019: TAVI has sustained health status benefits over surgery for...

A subanalysis of PARTNER 3 quality of life data demonstrated a modest, but significant, improvement in one-year disease-specific quality of life after transcatheter aortic...

TCT 2019: Benefits of complete revascularisation continue to accumulate over the...

A timing substudy of the COMPLETE trial has found that, compared with culprit-lesion only percutaneous coronary intervention (PCI), a strategy of non-culprit lesion PCI...

TCT 2019: COAPT finds MitraClip safety and efficacy is maintained at...

The MitraClip device (Abbott) continues to demonstrate safety and efficacy at three years in patients with heart failure and secondary mitral regurgitation (MR), findings...

TCT 2019: Acurate neo does not meet non-inferiority compared to Sapien...

The first randomised trial to compare the safety and efficacy of the Acurate neo transcatheter heart valve (Boston Scientific) with the Sapien 3 TAVI...

TCT 2019: Safety and efficacy of Portico valve noninferior to FDA-approved...

The Portico IDE study has found that 30-day safety and one-year effectiveness outcomes of a novel self-expanding transcatheter aortic valve implantation (TAVI) system for...

TCT 2019: Aspirin withdrawal after three months of dual antiplatelet therapy...

Data from the TWILIGHT study demonstrate that, compared to ticagrelor plus aspirin, ticagrelor monotherapy reduces bleeding events without increasing the risk of death, myocardial...

No device-related mortality at one year for India’s first trancatheter heart...

Ashok Seth (New Delhi, India) talks to BLearning at EuroPCR 2019 (21–24 May, Paris, France) about the MyVal-1 study which looked at the one-year clinical outcomes of India’s first...

Boston Scientific announces schedule of presentations at TCT 2019

Boston Scientific has announced the key data that will be presented at the Transcatheter Cardiovascular Therapeutics conference (TCT 2019; 25–29 September, San Francisco, USA). Data...

Corindus showcasing CorPath GRX system at TCT 2019

Corindus Is to showcase the CorPath GRX system at the Transcatheter Cardiovascular Therapeutics Conference (TCT 2019; 25–29 September, San Francisco, USA). CorPath GRX is...

Abbott starts trial to evaluate TriClip for percutaneous repair of tricuspid...

Abbott has announced its TRILUMINATE pivotal trial to evaluate the safety and effectiveness of the TriClip transcatheter tricuspid valve repair system for the treatment...

ESC 2019: Complete revascularisation superior to culprit lesion-only PCI in STEMI...

complete-revascularisation
A strategy of complete revascularisation was superior to culprit lesion-only percutaneous coronary intervention (PCI) in reducing the risk of cardiovascular death or myocardial infarction...

ECHSA 2019: CardioCel acellular bioscaffold handles well

Caner Salih (London, UK) talks to Cardiovascular News about the CardioCel bioscaffold (Admedus) and the benefits it has brought to his practice at Guy's...

Age alone should not preclude TAVI in patients aged ≥90 years

The clinical frailty score currently used to assess suitability for transcatheter aortic valve implantation (TAVI) requires further refinement, a study published in the American...

Unfilled prescriptions for PCSK9 inhibitors lead to higher rates of cardiovascular...

Patients whose prescription for PCSK9 inhibitors (proprotein convertase subtilisin kexin type 9 inhibitors) are either unfilled or rejected by insurance companies have a higher...

The findings on transcatheter aortic valve implantation in patients who are...

Recent low-risk trials for TAVI look set to expand its indications for use. Amar Krishnaswamy and Samir Kapadia assess the impact of the findings...

Medtronic enters into AI partnership for stroke care

Medtronic has entered into a partnership agreement with Viz.ai to accelerate the adoption of artificial intelligence software for stroke prevention and treatment in US...

TARGET BP I trial enrols its first patient

The first patient has been randomised in the TARGET BP I trial at the Piedmont Heart Institute in Atlanta, USA, to investigate the use...

Women with idiopathic intracranial hypertension at twice the risk of cardiovascular...

Women who suffer from idiopathic intracranial hypertension (IIH) have twice the risk of heart conditions and stroke than those of the same age and...

SAVR has lower mortality and MACCE than TAVI using first-generation devices...

Five-year results suggest that surgical aortic valve replacement (SAVR) is associated with lower rates of mortality and major adverse cardiac and cerebrovascular events (MACCE)...

The influence of technology and robotics in the catheterisation laboratory is...

Thanks to the use of robotics in healthcare, many procedures that were once highly invasive are now being performed using minimally invasive techniques, with...

Carillon Mitral Contour System reaches 1,000 implants for functional mitral regurgitation

  Cardiac Dimensions has announced in a press release that its Carillon Mitral Contour System has now been implanted in 1,000 patients in the USA,...

Medtronic announces global registry of HVAD thoracotomy implants

  Medtronic has announced plans for a global registry of its HeartWare HVAD System, following the release of two-year outcomes from the LATERAL clinical trial....

FEops HEARTguide wins CSI Highlight of the Year Award

FEops has won the CSI Frankfurt 2019’s Highlight of the Year Award for its FEops HEARTguide under the category of interventional imaging. A press...

New Liverpool Centre for Cardiovascular Science established

The Liverpool Centre for Cardiovascular Science, an alliance between academia and the NHS, was established to advance cardiovascular and stroke research and innovation locally,...

MeRes100 BRS demonstrates sustained safety and efficacy

Data from the MeRes-1 and MeRes-1 Extend clinical trials, released at EuroPCR 2019 (20–24 May, Paris, France), demonstrate sustained efficacy and safety for the...

Admedus’ announces favourable five-year outcomes for its CardioCel bioscaffold

Admedus has announced positive data from an independent study into the performance of its tissue engineered bovine pericardial implant CardioCel, which is used in...

PASCAL poised to rival MitraClip for safety and efficacy

PASCAL’s (Edwards Lifesciences) safety and efficacy may rival that of MitraClip (Abbott) for the treatment of mitral regurgitation (MR), according to data published in...

NICE issues recommendations on insertion of cerebral protection devices during TAVI

The National Institute for Health and Care Excellence (NICE) has released evidence-based recommendations on the percutaneous insertion of a cerebral protection device to prevent...

The evolution of PCR: milestones and achievements in its 30-year journey

2019 saw the 30th anniversary of EuroPCR, with 11,206 participants gathering in Paris. William Wijns, PCR chair, shares his perspective on how it has...

SCAI document provides advice on cath labs’ financial viability

The Society for Coronary Angiography (SCAI) has issued a statement, endorsed by the Alliance of Cardiovascular Professionals (ACVP), providing advice on the economics of...

Cardiologists can help to avert nuclear doomsday

Cardiologists can help to reduce the threat of nuclear war and move “the hands of the Doomsday Clock back from the midnight hour”, according...

PCR statement on TAVI signals “paradigm shift” in treatment of severe...

Evolving indications for the use of transcatheter aortic valve implantation (TAVI) have led to a series of “paradigm shifts” in the treatment of severe...

Early treatment with Helix system improves ejection fraction and symptoms

The Helix biotherapeutic delivery system (Biocardia), which delivers cell therapy to patients within four weeks of a heart attack, led to improved ejection fraction...

Biotronik announces positive data for Magmaris

A press release from Biotronik highlights data from the BIOSOLVE-IV registry outlining procedural success and a positive safety profile at one year for its...

FDA approves Cardioform ASD Occluder for the treatment of atrial septal...

The Cardioform ASD Occluder (Gore Medical) has received US Food and Drug Administration (FDA) premarket approval (PMA) for use in the percutaneous closure of...

EuroPCR 2019: Ultrasound pulmonary artery denervation “improving patient outcomes”

TROPHY1
Alex Rothman (Sheffield, UK) discusses the TROPHY1 study which looked at the safety and efficacy of ultrasound pulmonary artery denervation in patients with pulmonary...

American College of Cardiology names its first director of diversity and...

The American College of Cardiology (ACC) has announced the appointment of Ranna Parekh as its first director of diversity and inclusion. Parekh will work...

EuroPCR 2019: PARTNER 3 results “disruptive to our practice”

Thomas Modine (Lille, France) talks to Cardiovascular News about the PARTNER 3 trial comparing low-risk patients who had a transcatheter aortic valve replacement (TAVR)...

EuroPCR 2019: VIVALL pilot study shows promise for safe use of...

Early experience with the Allegra transcatheter heart valve (New Valve Technology) suggests it is safe for use in patients who have clinically significant degenerated...

EuroPCR 2019; TRILUMINATE suggests TriClip is safe and effective

Use of a TriClip (Abbott) for edge-to-edge repair in patients with tricuspid regurgitation appears to be a safe procedure, according to 30-day data from...

EuroPCR 2019: PCR issues statement on edge-to-edge repair in heart failure...

PCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI) issued a statement at EuroPCR 2019 (20–24 May, Paris, France) outlining the role of...

EuroPCR 2019: Consensus paper on intracoronary imaging focuses on acute coronary...

A consensus paper on the use of intracoronary imaging was released at EuroPCR 2019 (20–24 May, Paris, France) as a joint document with the...

Diagnosing coronary stenosis with diastolic pressure ratio measurements is equivalent to...

Using the diastolic pressure ratio (dPR) to identify ischaemia-producing lesions in patients with coronary artery disease provides a similar diagnostic performance to the instantaneous...

ClearFlow announces positive trial results and inclusion in ERAS guideline recommendations...

ClearFlow medical device company has announced positive clinical trial results for its PleuraFlow device, presented at the American Association for Thoracic Surgery (AATS) 99th...

USA needs to put greater emphasis on home-based cardiac rehabilitation

A Scientific Statement from the American Association of Cardiovascular and Pulmonary Rehabilitation, the American Heart Association, and the American College of Cardiology has called...

Keith Dawkins appointed as chief medical officer at Shockwave Medical

Shockwave Medical has appointed Keith D Dawkins as its chief medical officer. In a press release from the company, Dawkins states: “Given the challenges...

Avance steerable introducer given FDA 510(k) clearance

The AVANCE steerable introducer product family (BioCardia) has received US Food and Drug Administration (FDA) 510(k) clearance. The AVANCE device is designed to introduce...

Cordis expands its interventional cardiology portfolio with full US launch of...

Cordis, a Cardinal Health company, has announced the full US launch of its Radial 360 portfolio, offering a complete range of products to facilitate...

FDA approves extended duration of use for Impella 5.0 and Impella...

Abiomed has announced an expanded US Food and Drug Administration (FDA) approval for the Impella 5.0 and Impella LD heart pumps premarket approval (PMA)...

Virtue SEB given breakthrough device designation by FDA

The Virtue (Orchestra BioMed) sirolimus-eluting balloon for the treatment of coronary in-stent restenosis has secured breakthrough device designation from the US Food and Drug...

Bardy Diagnostics announces $35.5M funding injection

Bardy Diagnostics, provider of ambulatory cardiac monitoring technologies and custom data solutions, has announced it has raised $35.5 million (US) in Series B funding,...

ACC 2019: Less bleeding with one-month DAPT than standard therapy, with...

One-month dual antiplatelet therapy (DAPT) followed by 12 months of clopidogrel monotherapy leads to a greater reduction in bleeding events following percutaneous coronary intervention...

RADIANCE SOLO HTN finds greater blood pressure drop after renal denervation

Six-month "on-medication" results from the RADIANCE-HTN SOLO clinical trial have found that patients treated with the Paradise ultrasound denervation system (ReCor Medical Inc.) were...

Alirocumab receives EC approval in established atherosclerotic cardiovascular disease

The European Commission (EC) has approved the use of alirocumab (Praluent, Sanofi), a PCSK9 inhibitor, in adults with established atherosclerotic cardiovascular disease (ASCVD) to...

Richard Kovacs assumes presidency of the American College of Cardiology

Richard Kovacs has become the new president of the American College of Cardiology (ACC). He officially assumed his role during the convocation ceremony held...

2 Heart Research UK funds UCL research to improve baby congenital...

National charity, Heart Research UK has granted funding for an innovative research project with University College London, UK, and Great Ormond Street Hospital, London,...

AHA 2016: Elizabeth M McNally wins AHA prize for research into...

The American Heart Association (AHA) awarded its Basic Research Prize for 2016 to Elizabeth M McNally (Chicago, USA) for “Ground-breaking investigations of novel genetic...