Angela O'Neill

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Decreased ACE2 levels found in ageing and cardiovascular disease can increase...

The reduced levels of angiotensin converting enzyme (ACE) 2 associated with cardiovascular disease and increasing age lead to a higher susceptibility to greater disease...

PPE guidance for cardiology during COVID-19 pandemic operating in a “vacuum”...

Simon Ray, president of the British Cardiovascular Society (BCS), has told the COVID-19 Cardiovascular Conference that a lack of consistency in national guidance around...

Raised troponin and interleukin-6 levels are associated with a poor prognosis...

A raised troponin level in myocardial injury “greatly alters the prognosis adversely” in COVID-19 patients, Graham Cole (Imperial College Healthcare NHS Trust, London, UK)...

Italy, USA and the UK share their cardiology COVID-19 experiences in...

The COVID-19 Cardiovascular Conference, hosted as a live webinar by The Imperial College Network of Excellence in Vascular Science at Imperial College (London, UK),...

Daniel M Philbin Jr named new chair of the ACC board...

Daniel M Philbin Jr has been named chair of the American College of Cardiology (ACC) board of governors and secretary of the board of...

Live webinar on Thursday 2 April to share COVID-19 cardiovascular experience

The Imperial College Network of Excellence in Vascular Science at Imperial College London (UK) is to run a COVID-19 Cardiovascular Conference as a live...

Virtual ACC: PRECOMBAT finds PCI as good as CABG at 10...

The longest follow-up to date of patients with left main coronary artery disease (LMCAD) has found no significant differences in rates of death, myocardial...

Virtual ACC: Use of radial artery in heart bypass surgery improves...

Using the radial artery instead of the saphenous vein for patients undergoing coronary artery bypass graft (CABG) surgery leads to lower mortality and better...

Virtual ACC: Combining aspirin with rivaroxaban provides greater absolute risk reduction...

In stable atherosclerosis, a combination of aspirin plus rivaroxaban provided a similar relative degree of benefit on coronary, cerebrovascular, and peripheral endpoints in patients...

Virtual ACC: Aspirin plus rivaroxaban significantly lowers adverse events in PAD...

Treatment with aspirin plus rivaroxaban following lower extremity revascularisation in patients with peripheral arterial disease (PAD) leads to a 15% reduction in the risk...

Adapt clinical studies to alleviate effect of pandemic

A viewpoint in the Journal of the American Medical Association (JAMA) has offered potential solutions to modifying ongoing randomised clinical trials during the COVID-19...

Cardiac injury in COVID-19 patients linked with higher death rate

Cardiac injury is common among hospitalised patients with COVID-19, and is associated with a higher risk of in-hospital mortality, a study from Wuhan, China,...

CDRH adjusts working practices with medical device companies to deal with...

The US Food and Drug Administration’s (FDA) Center for Devices and Radiological Health (CDRH) has written to the medical device industry to outline its...

BCIS and BCS ratify NHS guidance for cardiology during COVID-19 pandemic

The British Cardiovascular Intervention Society (BCIS) and the British Cardiovascular Society (BCS) have endorsed guidance published by NHS England and NHS Improvement on the...

SCAI launches web section devoted to COVID-19 updates and cancels Scientific...

The Society for Cardiology and Angiography Interventions (SCAI) has set up a dedicated section on its website to keep interventional cardiologists up to date...

Duo device for tricuspid repair records first successful use in humans

CroíValve has announced the successful first human use of its Duo Tricuspid Coaptation Valve technology for tricuspid repair. The company says the procedure was...

One-third of critically ill COVID-19 patients in Washington State series developed...

A case series of US experience with COVID-19 has upheld suggestions of a link with cardiomyopathy, which developed in 33% of intensive care patients. In...

FDA issues new policy on remote monitoring devices for use during...

The US Food and Drug Administration (FDA) has issued an immediately-in-effect guidance that allows manufacturers of certain FDA-cleared non-invasive, vital-sign-measuring devices to expand their...

First report gives insight on impact of COVID-19 in heart transplant...

The first report on the impact of COVID-19 on heart transplant recipients has been published in The Journal of Heart and Lung Transplantation, outlining...

Frailty predicts greater death rate and higher costs after mitral valve...

ageing mitral valve surgery
Frailty is an independent predictor of morbidity, death, and increased costs after mitral valve replacement (MVR), a retrospective cohort study has determined. Writing in The...

SCAI issues advice for cath labs in light of COVID-19 pandemic

The Society for Cardiovascular Angiography and Interventions (SCAI) has written an open letter to members detailing options for managing patients in the cath lab...

Transcatheter heart valves are overlapping with coronary arteries

Data from a pilot imaging study of commissural alignment in trancatheter aortic valve implantation (TAVI) has found that more than 30–50% of cases had...

TriGUARD 3 given CE mark for embolic protection during TAVI

European CE mark has been awarded to the TriGUARD 3 cerebral embolic protection (CEP) device from Keystone Heart, a Venus Medtech Company. According to the...

Portola Pharmaceuticals unveils data on Andexxa in patients with multiple types...

Portola Pharmaceuticals announced new data that they say reinforces the value of Andexxa (coagulation factor Xa , inactivated-zhzo]. The company statement outlines that the...

Early quality of life increases or benefits in COAPT translate to...

Early improvement in health status for patients in the COAPT trial who had transcatheter mitral valve repair (TMVr) with the MitraClip (Abbott) was strongly...

PCI for chronic total occlusion less successful after bypass surgery

Patients who have a percutaneous coronary intervention (PCI) for chronic total occlusion following a coronary artery bypass graft (CABG) have worse outcomes than those...

Novel device “safely obliterates” left atrial appendage with minimal amount left...

The novel left atrial appendage (LAA) closure device Appligator (Append Medical) was a finalist in the 2019 ICI Innovation Award Competition (Innovation in Cardiovascular...

Approval of Tendyne TMVI device means physicians now have a portfolio...

Abbott made history in January when it became the first company in the world to receive market approval for a transcatheter mitral valve implantation...

ACC.20/WCC will be a virtual meeting

The American College of Cardiology Scientific Session Together with World Congress of Cardiology (ACC.20/WCC) is to run as a virtual meeting, following its cancellation...

Long-term exercise may lead to aortic enlargement and remodelling

Vascular remodelling may occur in response to sustained, regular exercise, suggests a study of aortic dilatation among long-term endurance athletes. Timothy W Churchill (Massachusetts...

Abbott receives CE mark for FlexNav delivery system

Abbott has received CE mark in Europe for the new FlexNav delivery system for the company's Portico transcatheter aortic valve implantation (TAVI) system. A...

New England Journal of Medicine to review EXCEL data

The New England Journal of Medicine (NEJM) has launched a review into the data from the EXCEL trial, two members of the BBC Newsnight...

Cardiovascular News Issue 56—February 2020: US Edition

issue
NOBLE finds PCI inferior to CABG at five years in left main disease EXCEL: repeat revascularisation after both CABG and PCI leads to...

Cardiovascular News Issue 56—February 2020

issue
NOBLE finds PCI inferior to CABG at five years in left main disease EXCEL: repeat revascularisation after both CABG and PCI leads to...

Paclitaxel coated balloons have lower risk of mortality in coronary arteries...

Paclitaxel drug coated balloons (DCB) for percutaneous treatment of coronary artery disease (CAD) are not associated with increased mortality, and longer term evaluation suggests...

ADVERTORIAL: Further data underline the critical role of Impella Heart Pumps...

Findings from an interim analysis of PROTECT III have added to the evidence for improved outcomes with Impella heart pumps in protected percutaneous coronary...

CryoLife given CE mark for On-X Ascending Aortic Prosthesis

CryoLife has received CE mark for the On-X Ascending Aortic Prosthesis (AAP), allowing resumed distribution in the European Union. The On-X AAP is indicated for...

FDA issues update on reducing the risk of patient infections during...

The US Food and Drug Administration (FDA) has cleared a new version of the LivaNova Heater-Cooler System 3T, which is used during cardiothoracic surgery...

First patients enrolled in PROACTIVE-HF trial of Cordella pulmonary artery pressure...

Endotronix has announced the enrollment of the first two patients in the PROACTIVE-HF trial. The trial is a premarket investigational device exempt (IDE) study...

Heart Research UK awards grant to University of Leeds to develop...

A research project at the University of Leeds aiming to identify new drug treatments for heart failure patients has been awarded a grant of...

CRT 2020: TAVI safe at 30 days in low-risk bicuspid aortic...

Transcatheter aortic valve implantation (TAVI) is safe in the short term in low-risk patients with symptomatic, severe bicuspid aortic stenosis (AS). Researchers also noted...

CRT 2020: Stage 3 kidney injury after TAVI leads to seven...

Patients who develop stage 3 acute kidney injury (AKI) following transcatheter aortic valve implantation (TAVI) have seven times higher adjusted one-year mortality than patients...

CRT 2020: Biotronik reports three-year results for Orsiro DES from BIOFLOW-V...

Biotronik has announced three-year data from the BIOFLOW-V trial, which were presented at the Cardiac Resynchronisation Therapy meeting (CRT 2020; 23–25 February, Washington DC,...

Edwards expands its Every Heartbeat Matters initiative

Edwards Life sciences initiative
Edwards Lifesciences has announced a new goal for its philanthropic initiative, Every Heartbeat Matters (EHM), which aims to improve the lives of 2.5 million...

Self-expanding and balloon-expandable valves are equally effective in high-risk TAVI

A comparison of newer generation self-expanding valves (SEV) and balloon-expandable valves (BEV) in high-risk patients with aortic stenosis undergoing transfemoral transcatheter aortic valve implantation...

Cardiovalve receives Breakthrough Device Designation for its transcatheter tricuspid valve replacement...

Cardiovalve
Cardiovalve has received US Food and Drug Administration (FDA) approval for an early feasibility study (EFS) of its transcatheter tricuspid valve replacement system for...

“Our goal is to treat more patients with mitral regurgitation”

Last month, Abbott announced US Food and Drug Administration (FDA) approval of a new trial—REPAIR MR—to evaluate the safety and efficacy of percutaneous edge-to-edge...

JIM 2020: Weigh up early and late events in EXCEL to...

Gregg W Stone (Icahn School of Medicine, Mount Sinai, New York, USA) addressed the EXCEL controversy today at the Joint Interventional Meeting (JIM 2020;...

Nicolas van Mieghem

Nicolas van Mieghem
Nicolas van Mieghem (professor of interventional cardiology, department of cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the Netherlands) shares his thoughts on a wide...

Orsiro Mission gets CE mark

Orsiro Mission DES
Biotronik has received CE mark certification for the Orsiro Mission drug-eluting stent (DES) system. According to a company statement, the next generation of the...

Philips announces DEFINE GPS study of PCI guided by integrated iFR...

Philips iFR Coregistration SyncVision
Philips has announced a new randomised controlled trial to assess percutaneous coronary intervention (PCI) guided by its coregistration platform, which combines data of an...

Transcatheter intervention can address “unmet need” in treatment of tricuspid valve...

Scott Lim (Charlottesville, USA) talks to BLearning Cardio at PCR London Valves 2019 (17–19 November, 2019; London, UK) about the challenges associated with transcatheter tricuspid valve intervention. Lim explains that the patient...

TAVI enthusiasm should be “tempered” in low-risk patients whilst durability concerns...

 Philippe Pibarot (Québec, Canada) talks to BLearning Cardio at PCR London Valves 2019 (17–19 November, 2019; London, UK) about the main data findings in the PARTNER 2 trial which evaluated...

Germany renews Revivent’s NUB reimbursement status 1 for 2020

BioVentrix has received renewal of the highest priority reimbursement in Germany for its Revivent TC transcatheter ventricular enhancement system. A company statement announced that...

CABG shows 10-year benefit over PCI in left main patients with...

Extended 10-year follow-up has demonstrated that in patients with a high SYNTAX score undergoing left main coronary artery (LMCA) revascularisation there is a clear...

EXCEL may damage relations between interventional cardiologists and cardiac surgeons

The debate over the results of EXCEL shows no sign of abating, and there seems to be a division between cardiac surgeons and interventional...

Portola Pharmaceuticals appoints Rajiv Patni as executive vice president and chief...

Rajiv Patni has been appointed as executive vice president and chief medical officer at Portola Pharmaceuticals, effective immediately. The company announced the appointment in...

Guy’s and St Thomas’ to merge with Royal Brompton & Harefield...

Guy’s and St Thomas’ and Royal Brompton & Harefield NHS Foundation Trusts are to merge. A joint statement from the two trusts has announced...

STS 2020: Harness the power of Twitter to give your research...

Highly-tweeted articles are 11 times more likely to be cited than less tweeted articles, Ourania Preventza (Division of Cardiothoracic Surgery, Baylor College of Medicine,...

STS 2020: Young patients with aortic valve disease do better with...

Open heart surgery remains the best option for young and middle-aged adults with aortic valve disease, for now; However, the use of transcatheter aortic...

STS 2020: Enhanced surgical recovery protocols will allow safe three-day discharge

Patients discharged three days after open heart surgery are not at increased risk of complications, an analysis of discharge patterns has shown. S Chris...

Low albumin, anaemia, and slow walking speed predict mortality after TAVI

The largest study to date of the role of frailty indices after transcatheter aortic valve implantation (TAVI) has demonstrated that the markers of low...

Further innovation and research is required for thrombus aspiration in PCI

The TASTE and TOTAL studies suggested that routine thombus aspiration in patients undergoing percutaneous coronary intervention (PCI) did not provide mortality benefit and may...

Emboline completes enrolment in SAFEPASS 2 clinical trial

SAFEPASS 2 clinical study of the Emboliner embolic protection catheter
Emboline has completed enrolment in its SAFEPASS 2 clinical study of the Emboliner embolic protection catheter. A press release from the company, which develops...

BioCardia gets FDA clearance for catheter to guide Helix delivery system

BioCardia has received US Food and Drug Administration (FDA) 510(k) clearance for its Morph DNA deflectable guide catheter, used to guide the Helix biotherapeutic...

Spartan Bioscience sets up European advisory board for precision medicine test...

Davide Capodanno, Gilles Montalescot, Marco Valgimigli and Dirk Sibbing
Spartan Bioscience, a maker of precision medicine diagnostic solutions, has established a new scientific advisory board (SAB) in Europe for cardiac stent patients that...

EXCEL finds repeat revascularisations following both CABG and PCI lead to...

A secondary analysis of repeat revascularisation in the EXCEL trial has found that it was associated with increased mortality after both percutaneous coronary intervention...

Abbott gets green light for trial on MitraClip in moderate surgical...

Abbott has announced that the US Food and Drug Administration (FDA) has approved a first-of-its-kind clinical trial that will compare the effectiveness of Abbott's...

Self-expanding valves show good haemodynamic performance in small annuli

A retrospective registry comparing four self-expanding transcatheter heart valves has demonstrated good haemodynamic performance in small aortic annuli, with low post-procedure gradients, large orifice...

FDA approves Abbott heart pump for less invasive surgical approach

Abbott has announced US Food and Drug Administration (FDA) approval of a new alternative surgical technique for Abbott's HeartMate 3 heart pump that the...

Jean-Claude Dubacher named chairman and CEO of B Braun Medical

B Braun has announced the appointment of Jean-Claude Dubacher as chairman and CEO. Dubacher joined B Braun on 1 August 2019 as president, B...

Proximo Medical to partner with CeloNova Biosciences

Proximo Medical is to partner with CeloNova Biosciences, supplier of the COBRA PzF nanocoated coronary stent (NCS), in select US markets. Carl St Bernard, chief...

EXCEL: EACTS reaches out to trial investigators to “resolve concerns”, as...

The European Association of Cardio-Thoracic Surgeons (EACTS) has issued a statement reaching out to EXCEL investigators to “offer assistance” in resolving concerns raised about...

EXCEL: EACTS explains its decision-making on left-main guidelines, and AATS calls...

The European Association of Cardio-Thoracic Surgeons (EACTS) has published a detailed account of the process that led to its “unprecedented” decision to reverse its...

NOBLE finds PCI inferior to CABG at five years in left...

Corresponding author Evald Hoj Christiansen
Five-year data from the NOBLE trial have confirmed its earlier findings that in patients with unprotected left main coronary disease the risk of major...

EACTS and STS announce strategic partnership

The Society for Thoracic Surgeons (STS) and the European Association of Cardio-Thoracic Surgeons (EACTS) have announced that they will participate in a strategic collaboration. A...

Routine anticoagulation with rivaroxaban after TAVI harmful: GALILEO trial results

George Dangas (Mount Sinai Hospital, New York, USA) told delegates in a late-breaking trial session at the American Heart Association Scientific Sessions (AHA 2019;...

InnovHeart appoints Brent Ratz as independent member of the board

InnovHeart—a developer of novel transcatheter mitral valve replacement (TMVR) systems—has appointed medical device entrepreneur J Brent Ratz as nonexecutive independent member of its Board...

Bioventrix announces positive one-year outcomes for Revivent TC system

Bioventrix has announced online publication of positive one-year results from its CE mark study of the Revivent TC System in the European Journal of...

Further innovation and research is required for thrombus aspiration in PCI

The TASTE and TOTAL studies suggested that routine thombus aspiration in patients undergoing percutaneous coronary intervention (PCI) did not provide mortality benefit and may...

AHA 2019: ISCHEMIA shows no benefit for revascularisation in patients with...

The largest trial to date to compare revascularisation with a conservative strategy in patients with stable ischaemic heart disease has found no additional benefit...

AHA 2019: Preprocedural COLCHICINE-PCI finds a lowering of inflammation, but no...

Preprocedural administration of an oral colchicine load does not reduce the risk of myocardial injury or 30-day major adverse cardiovascular events (MACE) in patients...

PCR London Valves 2019: Meril unveils positive data for Myval

Meril has announced positive data on its Myval Transcatheter Heart Valve System at PCR London Valves 2019 (17–19 November 2019). A follow-up of 100...

Corindus completes first transcontinental simulated telerobotic PCI procedures over 5G, fibre,...

Corindus has announced the completion of the first multicity, transcontinental percutaneous coronary intervention (PCI) simulations in the USA over three network connection types: 5G...

Revivent transcatheter system receives Breakthrough Device Designation from the FDA

The Revivent transcatheter ventricular enhancement system (Bioventrix) has been granted Breakthrough Device Designation by the US Food and Drug Administration (FDA). The Revivent investigational...

PCR London Valves 2019: PARTNER 2 analysis shows Sapien 3 valve...

An analysis of structural valve deterioration in the PARTNER 2A trial has found that the third generation Sapien 3 transcatheter heart valve (Edwards Lifesciences)...

PCR London Valves 2019: TRILUMINATE shows safety and efficacy of TriClip...

The use of TriClip (Abbott) for edge-to-edge repair in tricuspid regurgitation (TR) remains safe and effective at one year, preliminary outcomes from the TRILUMINATE...

PCR London Valves 2019: A simple algorithm can reduce unnecessary pacemaker...

Permanent pacemaker implantation (PPI) after transcatheter aortic valve implantation (TAVI) is associated with increased mortality at six years, particularly in patients who are pacemaker...

PCR London Valves 2019: One-year survival better with Mitra Clip than...

A single-centre real world experience has found that the vast majority of patients with severe mitral regurgitation (MR) were not eligible for inclusion in...

More focus needed on best medical therapy and perfusion imaging for...

The mortality risk for patients with critical limb ischaemia (CLI) has not changed over the last few decades, despite advances in cardiovascular medicine that...

Shockwave commences IVL study to support regulatory approval in Japan

Shockwave Medical has initiated the DISRUPT CAD IV study of its intravascular lithotripsy (IVL) system with the aim of using data from the study...

“Cuffless” system to monitor blood pressure could replace traditional methods

A wrist-based optical blood pressure monitor has the potential to replace cuff monitoring systems for ambulatory blood pressure, suggests a study in the journal...

Multiphase and early systolic phase CT screening in TMVR superior to...

The use of multiphase computed tomography (CT) assessment, particularly during the early systolic phase, of the neo-left ventricular outflow tract (LVOT) is a better...

GLOBAL LEADERS: no sex-difference in mortality or MI rates two years...

A prespecified subgroup analysis of the GLOBAL LEADERS trial has found no between-sex difference in the risk of two-year all-cause mortality or new Q-wave...

Ehtisham Mahmud

The 2019–20 president of the Society for Cardiovascular Angiography and Interventions (SCAI) Ehtisham Mahmud (division chief, Cardiovascular Medicine, UC San Diego, San Diego, USA)...

Pre-TAVI aortic regurgitation aids survival post-TAVI in mixed aortic valve disease...

Patients who have mixed aortic valve disease with pre-existing aortic regurgitation have better survival rates following transcatheter aortic valve implantation (TAVI) than those who...

US FDA grants Breakthrough Device designation to CorFlow Infusion System

CorFlow Therapeutics has announced that the company has been granted Breakthrough Device designation from the US Food and Drug Administration (FDA) for its Controlled...

Cardionovum’s coronary DCB receives regulatory approval in China

Cardionovum's Restore paclitaxel-coated balloon for coronary applications has received market approval for use in China. It can be used in treating two indications: in-stent...

Corindus’ stockholders approve acquisition by Siemens Healthineers

The stockholders of Corindus Vascular Robotics have approved the adoption of the agreement and plan of merger that was drawn up in August by...

Two further studies support three-month DAPT following PCI

Further evidence for a shorter duration of dual antiplatelet therapy (DAPT) in patients implanted with a drug eluting stent has been provided with the...

Patients with angiographically-intermediate coronary lesions

Using optical coherence tomography (OCT)-to guide percutaneous coronary intervention (PCI) is associated with a lower occurrence of major adverse cardiac events (MACE) or significant...

Diversity strategies in cardiology are not working, study finds

Different strategies are needed to address the continuing lack of diversity in the US cardiology workforce, say the authors of a cross-sectional study which...

Device deaths are under reported, says research letter

patient deaths are under reported said Rita Redberg
A study published as a research letter in JAMA Internal Network has found a “substantial misclassification” of patient deaths for the Sapien 3 and...

Shockwave study demonstrates strong safety and procedural success of coronary IVL...

Shockwave Medical, a company which provides intravascular lithotripsy (IVL) to treat complex calcified cardiovascular disease, unveiled the results of the DISRUPT CAD II study,...

International medical graduates in US cardiovascular care are vital to healthcare...

William W Pinsky and Mandeep R Mehra explain to Cardiovascular News how international medical graduates contribute to both their adopted country and their country...

Admedus sells CardioCel and VacsuCel to focus on TAVI

Admedus has sold the distribution rights to its CardioCel and VascuCel product range for $A36.2 million to US-based LeMaitre Vascular. A press release from...

Penumbra announces enrolment of first patient in study of mechanical power...

Penumbra has announced the enrolment of the first patient into the CHEETAH study, a prospective, multicentre US study to evaluate the safety and performance...

Douglas Drachman named as next vice chair of American College of...

Douglas Drachman has been selected as the next vice chair of the American College of Cardiology’s Annual Scientific Session. Drachman will serve as vice...

Abiomed announces PROTECT III clinical data for protected PCI with Impella

Abiomed has announced the results of PROTECT III, an ongoing, prospective, single-arm US Food and Drug Administration (FDA) post-market approval (PMA) study for Impella...

AccuCinch ventricular repair system associated with favourable safety profile at 30...

Data from an interim analysis of heart failure patients treated in the CorCinch FMR study show, a press release reports, that the AccuCinch ventricular...

TCT 2019: Apixaban plus a P2Y12 inhibitor is the optimal strategy...

A prespecified analysis of data from the AUGUSTUS study, released at late-breaking session at the Transcatheter Cardiovascular Therapeutics scientific symposium (TCT 2019; 25–29 September,...

CE mark granted to the Gore Cardioform ASD Occluder for the...

The Gore Cardioform Occluder for atrial septal defects (ASD) has received CE mark in Europe, the company has announced, stating that the move was...

Transseptal puncture techniques must be mastered if physicians wish to perform...

Interest in transseptal puncture has surged with the development of structural interventions for the left side of the heart. Francesco Maisano provides an update...

Endotronix closes expanded series D financing round of US$70 million for...

Endotronix has announced the expansion of its series D financing round, bringing the total to US$70 million. The expansion syndicate includes new investment from...

TCT 2019: Resolute Onyx noninferior to BioFreedom in high bleeding risk...

ONYX ONE, the first randomised trial to compare a durable polymer drug-eluting stent to a polymer-free drug-coated stent in patients at high risk of...

TCT 2019: TAVI has sustained health status benefits over surgery for...

A subanalysis of PARTNER 3 quality of life data demonstrated a modest, but significant, improvement in one-year disease-specific quality of life after transcatheter aortic...

TCT 2019: Benefits of complete revascularisation continue to accumulate over the...

A timing substudy of the COMPLETE trial has found that, compared with culprit-lesion only percutaneous coronary intervention (PCI), a strategy of non-culprit lesion PCI...

TCT 2019: COAPT finds MitraClip safety and efficacy is maintained at...

The MitraClip device (Abbott) continues to demonstrate safety and efficacy at three years in patients with heart failure and secondary mitral regurgitation (MR), findings...

TCT 2019: Acurate neo does not meet non-inferiority compared to Sapien...

The first randomised trial to compare the safety and efficacy of the Acurate neo transcatheter heart valve (Boston Scientific) with the Sapien 3 TAVI...

TCT 2019: Safety and efficacy of Portico valve noninferior to FDA-approved...

The Portico IDE study has found that 30-day safety and one-year effectiveness outcomes of a novel self-expanding transcatheter aortic valve implantation (TAVI) system for...

TCT 2019: Aspirin withdrawal after three months of dual antiplatelet therapy...

Data from the TWILIGHT study demonstrate that, compared to ticagrelor plus aspirin, ticagrelor monotherapy reduces bleeding events without increasing the risk of death, myocardial...

No device-related mortality at one year for India’s first trancatheter heart...

Ashok Seth (New Delhi, India) talks to BLearning at EuroPCR 2019 (21–24 May, Paris, France) about the MyVal-1 study which looked at the one-year clinical outcomes of India’s first...

Boston Scientific announces schedule of presentations at TCT 2019

Boston Scientific has announced the key data that will be presented at the Transcatheter Cardiovascular Therapeutics conference (TCT 2019; 25–29 September, San Francisco, USA). Data...

Corindus showcasing CorPath GRX system at TCT 2019

Corindus Is to showcase the CorPath GRX system at the Transcatheter Cardiovascular Therapeutics Conference (TCT 2019; 25–29 September, San Francisco, USA). CorPath GRX is...

Abbott starts trial to evaluate TriClip for percutaneous repair of tricuspid...

Abbott has announced its TRILUMINATE pivotal trial to evaluate the safety and effectiveness of the TriClip transcatheter tricuspid valve repair system for the treatment...

ESC 2019: Complete revascularisation superior to culprit lesion-only PCI in STEMI...

complete-revascularisation
A strategy of complete revascularisation was superior to culprit lesion-only percutaneous coronary intervention (PCI) in reducing the risk of cardiovascular death or myocardial infarction...

ECHSA 2019: CardioCel acellular bioscaffold handles well

Caner Salih (London, UK) talks to Cardiovascular News about the CardioCel bioscaffold (Admedus) and the benefits it has brought to his practice at Guy's...

Age alone should not preclude TAVI in patients aged ≥90 years

The clinical frailty score currently used to assess suitability for transcatheter aortic valve implantation (TAVI) requires further refinement, a study published in the American...

Unfilled prescriptions for PCSK9 inhibitors lead to higher rates of cardiovascular...

Patients whose prescription for PCSK9 inhibitors (proprotein convertase subtilisin kexin type 9 inhibitors) are either unfilled or rejected by insurance companies have a higher...

The findings on transcatheter aortic valve implantation in patients who are...

Recent low-risk trials for TAVI look set to expand its indications for use. Amar Krishnaswamy and Samir Kapadia assess the impact of the findings...

Medtronic enters into AI partnership for stroke care

Medtronic has entered into a partnership agreement with Viz.ai to accelerate the adoption of artificial intelligence software for stroke prevention and treatment in US...

TARGET BP I trial enrols its first patient

The first patient has been randomised in the TARGET BP I trial at the Piedmont Heart Institute in Atlanta, USA, to investigate the use...

Women with idiopathic intracranial hypertension at twice the risk of cardiovascular...

Women who suffer from idiopathic intracranial hypertension (IIH) have twice the risk of heart conditions and stroke than those of the same age and...

SAVR has lower mortality and MACCE than TAVI using first-generation devices...

Five-year results suggest that surgical aortic valve replacement (SAVR) is associated with lower rates of mortality and major adverse cardiac and cerebrovascular events (MACCE)...

The influence of technology and robotics in the catheterisation laboratory is...

Thanks to the use of robotics in healthcare, many procedures that were once highly invasive are now being performed using minimally invasive techniques, with...

Carillon Mitral Contour System reaches 1,000 implants for functional mitral regurgitation

  Cardiac Dimensions has announced in a press release that its Carillon Mitral Contour System has now been implanted in 1,000 patients in the USA,...

Medtronic announces global registry of HVAD thoracotomy implants

  Medtronic has announced plans for a global registry of its HeartWare HVAD System, following the release of two-year outcomes from the LATERAL clinical trial....

FEops HEARTguide wins CSI Highlight of the Year Award

FEops has won the CSI Frankfurt 2019’s Highlight of the Year Award for its FEops HEARTguide under the category of interventional imaging. A press...

New Liverpool Centre for Cardiovascular Science established

The Liverpool Centre for Cardiovascular Science, an alliance between academia and the NHS, was established to advance cardiovascular and stroke research and innovation locally,...

MeRes100 BRS demonstrates sustained safety and efficacy

Data from the MeRes-1 and MeRes-1 Extend clinical trials, released at EuroPCR 2019 (20–24 May, Paris, France), demonstrate sustained efficacy and safety for the...

Admedus’ announces favourable five-year outcomes for its CardioCel bioscaffold

Admedus has announced positive data from an independent study into the performance of its tissue engineered bovine pericardial implant CardioCel, which is used in...

PASCAL poised to rival MitraClip for safety and efficacy

PASCAL’s (Edwards Lifesciences) safety and efficacy may rival that of MitraClip (Abbott) for the treatment of mitral regurgitation (MR), according to data published in...

NICE issues recommendations on insertion of cerebral protection devices during TAVI

The National Institute for Health and Care Excellence (NICE) has released evidence-based recommendations on the percutaneous insertion of a cerebral protection device to prevent...

The evolution of PCR: milestones and achievements in its 30-year journey

2019 saw the 30th anniversary of EuroPCR, with 11,206 participants gathering in Paris. William Wijns, PCR chair, shares his perspective on how it has...

SCAI document provides advice on cath labs’ financial viability

The Society for Coronary Angiography (SCAI) has issued a statement, endorsed by the Alliance of Cardiovascular Professionals (ACVP), providing advice on the economics of...

Cardiologists can help to avert nuclear doomsday

Cardiologists can help to reduce the threat of nuclear war and move “the hands of the Doomsday Clock back from the midnight hour”, according...

PCR statement on TAVI signals “paradigm shift” in treatment of severe...

Evolving indications for the use of transcatheter aortic valve implantation (TAVI) have led to a series of “paradigm shifts” in the treatment of severe...

Early treatment with Helix system improves ejection fraction and symptoms

The Helix biotherapeutic delivery system (Biocardia), which delivers cell therapy to patients within four weeks of a heart attack, led to improved ejection fraction...

Biotronik announces positive data for Magmaris

A press release from Biotronik highlights data from the BIOSOLVE-IV registry outlining procedural success and a positive safety profile at one year for its...

FDA approves Cardioform ASD Occluder for the treatment of atrial septal...

The Cardioform ASD Occluder (Gore Medical) has received US Food and Drug Administration (FDA) premarket approval (PMA) for use in the percutaneous closure of...

EuroPCR 2019: Ultrasound pulmonary artery denervation “improving patient outcomes”

TROPHY1
Alex Rothman (Sheffield, UK) discusses the TROPHY1 study which looked at the safety and efficacy of ultrasound pulmonary artery denervation in patients with pulmonary...

American College of Cardiology names its first director of diversity and...

The American College of Cardiology (ACC) has announced the appointment of Ranna Parekh as its first director of diversity and inclusion. Parekh will work...

EuroPCR 2019: PARTNER 3 results “disruptive to our practice”

Thomas Modine (Lille, France) talks to Cardiovascular News about the PARTNER 3 trial comparing low-risk patients who had a transcatheter aortic valve replacement (TAVR)...

EuroPCR 2019: VIVALL pilot study shows promise for safe use of...

Early experience with the Allegra transcatheter heart valve (New Valve Technology) suggests it is safe for use in patients who have clinically significant degenerated...

EuroPCR 2019; TRILUMINATE suggests TriClip is safe and effective

Use of a TriClip (Abbott) for edge-to-edge repair in patients with tricuspid regurgitation appears to be a safe procedure, according to 30-day data from...

EuroPCR 2019: PCR issues statement on edge-to-edge repair in heart failure...

PCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI) issued a statement at EuroPCR 2019 (20–24 May, Paris, France) outlining the role of...

EuroPCR 2019: Consensus paper on intracoronary imaging focuses on acute coronary...

A consensus paper on the use of intracoronary imaging was released at EuroPCR 2019 (20–24 May, Paris, France) as a joint document with the...

Diagnosing coronary stenosis with diastolic pressure ratio measurements is equivalent to...

Using the diastolic pressure ratio (dPR) to identify ischaemia-producing lesions in patients with coronary artery disease provides a similar diagnostic performance to the instantaneous...

ClearFlow announces positive trial results and inclusion in ERAS guideline recommendations...

ClearFlow medical device company has announced positive clinical trial results for its PleuraFlow device, presented at the American Association for Thoracic Surgery (AATS) 99th...

USA needs to put greater emphasis on home-based cardiac rehabilitation

Randal J Thomas looks to home-based cardiac rehabilitation
A Scientific Statement from the American Association of Cardiovascular and Pulmonary Rehabilitation, the American Heart Association, and the American College of Cardiology has called...

Keith Dawkins appointed as chief medical officer at Shockwave Medical

Shockwave Medical has appointed Keith D Dawkins as its chief medical officer. In a press release from the company, Dawkins states: “Given the challenges...

Avance steerable introducer given FDA 510(k) clearance

The AVANCE steerable introducer product family (BioCardia) has received US Food and Drug Administration (FDA) 510(k) clearance. The AVANCE device is designed to introduce...

Cordis expands its interventional cardiology portfolio with full US launch of...

Cordis, a Cardinal Health company, has announced the full US launch of its Radial 360 portfolio, offering a complete range of products to facilitate...

FDA approves extended duration of use for Impella 5.0 and Impella...

impella in preventing heart failure in stemi patients
Abiomed has announced an expanded US Food and Drug Administration (FDA) approval for the Impella 5.0 and Impella LD heart pumps premarket approval (PMA)...

Virtue SEB given breakthrough device designation by FDA

The Virtue (Orchestra BioMed) sirolimus-eluting balloon for the treatment of coronary in-stent restenosis has secured breakthrough device designation from the US Food and Drug...

Bardy Diagnostics announces $35.5M funding injection

Bardy Diagnostics, provider of ambulatory cardiac monitoring technologies and custom data solutions, has announced it has raised $35.5 million (US) in Series B funding,...

ACC 2019: Less bleeding with one-month DAPT than standard therapy, with...

One-month dual antiplatelet therapy (DAPT) followed by 12 months of clopidogrel monotherapy leads to a greater reduction in bleeding events following percutaneous coronary intervention...

RADIANCE SOLO HTN finds greater blood pressure drop after renal denervation

Six-month "on-medication" results from the RADIANCE-HTN SOLO clinical trial have found that patients treated with the Paradise ultrasound denervation system (ReCor Medical Inc.) were...

Alirocumab receives EC approval in established atherosclerotic cardiovascular disease

The European Commission (EC) has approved the use of alirocumab (Praluent, Sanofi), a PCSK9 inhibitor, in adults with established atherosclerotic cardiovascular disease (ASCVD) to...

Richard Kovacs assumes presidency of the American College of Cardiology

Richard Kovacs has become the new president of the American College of Cardiology (ACC). He officially assumed his role during the convocation ceremony held...

2 Heart Research UK funds UCL research to improve baby congenital...

National charity, Heart Research UK has granted funding for an innovative research project with University College London, UK, and Great Ormond Street Hospital, London,...

AHA 2016: Elizabeth M McNally wins AHA prize for research into...

The American Heart Association (AHA) awarded its Basic Research Prize for 2016 to Elizabeth M McNally (Chicago, USA) for “Ground-breaking investigations of novel genetic...