Cardiac MRI effective at identifying myocarditis in athletes

Study authors Saurabh Rajpal and Curt Daniels

Cardiac magnetic resonance imaging (MRI) is effective in identifying inflammation of the heart muscle in athletes and can help determine when those who have recovered from COVID-19 can safely return to play in competitive sports, according to a study by Saurabh Rajpal and Curt Daniels (Ohio State University Wexner Medical Center, Columbus, USA), published online in JAMA Cardiology.

The authors examined 26 COVID-19 positive male and female competitive college athletes for signs of myocarditis, a rare disease that can cause heart failure and sudden cardiac death. Most cases of myocarditis, which is usually caused by a viral infection, happen in young adults with males affected more than females. Recent studies have shown myocardial inflammation in patients who recovered from COVID-19. Twelve of the athletes studied by Ohio State researchers reported mild symptoms of COVID-19 and the rest were asymptomatic.

Recently published protocols recommend the use of a combination of clinical examination, echocardiogram, electrocardiogram  and a blood test to help with diagnosis of myocarditis in athletes prior to return to competitive play. The researchers used all of these methods as well as cardiac MRI, which they found to be effective in identifying myocardial inflammation not picked up by other methods.

“This is the first study to systematically investigate the use of cardiac MRI in competitive athletes recovered from COVID-19 infection. CMR has the potential to identify a high-risk group for adverse outcomes and may, importantly, risk stratify athletes for safe participation, as CMR mapping techniques have a high negative predictive value to rule out myocarditis,” said Rajpal, who led the study.

In the study, four athletes (15%) were shown to possibly have myocarditis by MRI criteria. In addition to these four, eight others had evidence of scar tissue, suggesting either prior myocardial injury or normal athletic adaptation of the heart.

“It’s not known what caused the scar tissue in those eight, or if it was related to having COVID-19,” Rajpal said. “Additionally, the cardiac MRI ruled out myocarditis for all athletes without MRI evidence of inflammation, allowing them to return to playing sports.”

“The public should be aware of these findings and know the symptoms of heart disease with COVID-19 infection. As people begin to exercise after recovering from the virus, any chest pain, shortness of breath or abnormal heart beats should be evaluated by a doctor,” said Daniels, the study’s co-author.

The study’s authors recommend more research on CMR screening, including long-term follow-ups with athletes and control populations.


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